Anti-TP Rabbit Polyclonal Antibody (Alexa Fluor® 647)
Catalog # BOSSBS-3809R-A647
Supplier: Bioss
Specifications
- Antibody type:Primary
- Antigen name:Thymidine Phosphorylase
- Antigen symbol:TP
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 647
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human
- Cross adsorption:No
- Form:liquid
- Gene ID:1890
- Antigen synonyms:TP|MNGIE|PDECGF|ECGF1|hPD-ECGF|tdRPase|MEDPS1|gliostatin|ECGF|MTDPS1
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Purification:Purified by Protein A
- Pk:100 µl
Specifications
About this item
In the presence of inorganic orthophosphate, the platelet-derived endothelial growth factor (PD-ECGF) thymidine phosphorylase (TP) (gliostatin) catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: TP
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human