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Human TNFRSF13B ELISA kit
Human TNFRSF13B ELISA kit
  BIRBORB138089-96
 :  Biorbyt
 :  
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Human TNFRSF13B ELISA kit
  BIRBORB138089-96
 :  Biorbyt
 :  

 

  • Pk:
    96
  • Primary antibody reactivity:
    Human
  • Description:
    Human TNFRSF13B ELISA Kit
  • Detection range:
    93,8 - 6000 pg/ml
  • Sensitivity:
    <10 pg/ml

 

 

Human TNFRSF13B ELISA Kit for the quantitative detection of human tumour necrosis factor receptor superfamily member 13B (TNFRSF13B, TACI) in cell culture supernates, serum and plasma (heparin, EDTA).

TNFRSF13B is a transmembrane receptor protein found predominantly on the surface of B cells, which are an important part of the immune system. TACI controls T cell-independent B cell antibody responses, isotype switching, and B cell homeostasis. TACI is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It was originally discovered because of its ability to interact with calcium-modulator and cyclophilin ligand (CAML). TACI was later found to play a crucial role in humoral immunity by interacting with two members of the TNF family: BAFF and APRIL. These proteins signal through TACI inducing activation of several transcription factors including NFAT, AP-1, and NF-kappa-B which then modulate cellular activities. Defects in the function of TACI can lead to immune system diseases.