Recognizes a protein of 55 kDa, identified as CD4. It is a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus. This protein is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.This MAb was characterized as human CD4 antibody at II and IV International Workshop on Human Leukocyte Differentiation Antigens.
Type: Primary
Antigen: CD4
Clonality: Monoclonal
Clone: EDU-2
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG2a kappa
Reactivity: Chimpanzee, Human, Macaca artctoids, Orangutan
- Catalog No:
- BNC040345-500
- BNC040345-100
- Antigen symbol:
- CD4
- CD4
- Antigen synonyms:
- L3T4|T cell differentiation antigen L3T4|Leu3|T-cell surface antigen T4/Leu-3|p55|T cell antigen T4/LEU3|Lymphocyte antigen CD4|Ly-4|T-cell surface glycoprotein CD4
- L3T4|T cell differentiation antigen L3T4|Leu3|T-cell surface antigen T4/Leu-3|p55|T cell antigen T4/LEU3|Lymphocyte antigen CD4|Ly-4|T-cell surface glycoprotein CD4
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- CF® 405S
- CF® 405S
- Clone:
- Clone EDU-2
- Clone EDU-2
- Reactivity:
- Macaca artctoids, Orangutan, Chimpanzee, Human
- Macaca artctoids, Orangutan, Chimpanzee, Human
- Host:
- Mouse
- Mouse
- Gene ID:
- 631659
- 631659
- Isotype:
- IgG2a kappa
- IgG2a kappa
- ImmunoFluorescence:
- Yes
- Yes
- Concentration:
- 0,1 mg/ml
- 0,1 mg/ml
- Storage buffer:
- PBS/0,1% BSA/0,05% azide
- PBS/0,1% BSA/0,05% azide