Human TNFRSF17 ELISA Kit for the quantitative detection of human tumour necrosis factor receptor superfamily member 17 (TNFRSF17, BCMA) in cell culture supernates, serum and plasma (heparin, EDTA).

TNFRSF17 is a protein that in humans is encoded by the TNFRSF17 gene. The protein encoded by this gene is a member of the TNF-receptor superfamily and is mapped to 16p13.13. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumour necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.