About this item
The RM134L antibody recognizes CD252, also known as OX-40 Ligand or CD134 Ligand, a member of the TNF superfamily that is present on the surface of antigen presenting cells and activated B lymphocytes. The OX-40 Ligand interacts with OX-40 (CD134) which is expressed primarily on activated T cells. This costimulatory interaction leads to increased proliferation and IL-2 production responses of activated T cells, and at the same time enhances proliferation and immunoglobulin secretion by activated B cells.
The RM134L antibody is useful for flow cytometric detection of CD252 on stimulated mouse splenocytes. It has also been reported to block the costimulatory activity of OX-40 Ligand. Please choose the appropriate format for each application.
Type: Primary
Antigen: CD252 (OX40 Ligand)
Clonality: Monoclonal
Clone: RM134L
Conjugation: APC (Allophycocyanine)
Epitope:
Host: Rat
Isotype: IgG2b, kappa
Reactivity: Mouse
Specifications
- Catalog No:
- 20-5905-U100
- 20-5905-U025
- Antigen symbol:
- TNFSF4
- TNFSF4
- Antigen name:
- Tumor Necrosis Factor Superfamily Member 4
- Tumor Necrosis Factor Superfamily Member 4
- Antigen synonyms:
- TNFSF4|CD134L|OX-40L|TXGP1|OX40L|OX4OL|Glycoprotein Gp34|CD252|Tumor necrosis factor ligand superfamily member 4|GP34
- TNFSF4|CD134L|OX-40L|TXGP1|OX40L|OX4OL|Glycoprotein Gp34|CD252|Tumor necrosis factor ligand superfamily member 4|GP34
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- APC (Allophycocyanin)
- APC (Allophycocyanin)
- Clone:
- RM134L
- RM134L
- Reactivity:
- Mouse
- Mouse
- Host:
- Rat
- Rat
- Gene ID:
- 22164
- 22164
- Isotype:
- IgG2b kappa
- IgG2b kappa
- Flow cytometry:
- Yes
- Yes
- Storage temperature:
- +2 °C to +8 °C, protected from light
- +2 °C to +8 °C, protected from light