Specifications
- Antibody type:Primary
- Antigen name:Acid sensing (proton-gated) ion channel 3
- Antigen symbol:ASIC3
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Epitope:N-Terminal
- Cross adsorption:No
- Form:Lyophilized
- Antigen synonyms:ASICs3, ACCN 3, ACCN3, ASIC3_HUMAN, Acid sensing ion channel 3, Acid-sensing ion channel 3, Amiloride sensitive cation channel 3, Amiloride sensitive cation channel 3 testis, Amiloride-sensitive cation channel 3, ASIC 3, ASIC3, DRASIC, hASIC 3, hASIC3, hTNaC 1, hTNaC1, Modulatory subunit of ASIC 2a, Modulatory subunit of ASIC2a, Neuronal amiloride sensitive cation channel 3, Neuronal amiloride-sensitive cation channel 3, Proton gated cation channel subunit, SLNAC 1, SLNAC1, Testis sodium channel 1, TNaC 1, TNaC1.
- Amino acid number:56 to 73
- UniProtKB:Q9UHC3
- Sequence:FLYQVAERVRYYREFHHQ
- Storage temperature:–20 °C
- Shipping temperature:Ice
- Immunogen:A synthetic peptide corresponding to a sequence at the N-terminus of human ASIC3 (56-73aa FLYQVAERVRYYREFHHQ), different from the related rat and mouse sequences by two amino acids.
- Purification:purified by immunogen affinity purification
- Size:100 µg
- Pk:0,1 mg
Specifications
About this item
Rabbit IgG polyclonal antibody for Acid-sensing ion channel 3(ASIC3) detection. Tested with WB in Human;Mouse;Rat.
ASIC3(Acid-Sensing Ion Channel3), also known as TESTIS SODIUM CHANNEL 1(TNAC1) or DORSAL ROOT ACID-SENSING ION CHANNEL(DRASIC), is a protein that in humans is encoded by the ASIC3 gene. ASIC3 belongs to a family of acid-sensing channel proteins that are structurally related to epithelial sodium channel proteins and support acid-activated membrane currents. By radiation hybrid analysis, de Weille et al.(1998) mapped the ACCN3 gene to chromosome 7q35. De Weille et al.(1998) found that human ASIC3 supported an H(+)-gated cation current in COS cells with kinetics similar to those of rat Asic3. Babinski et al.(1999) expressed homomeric human ASIC3 channels in Xenopus oocytes and found that rapid reduction in extracellular pH resulted in a biphasic response characterized by a fast and rapidly desensitizing current followed by a slow and sustained current that returned to baseline only on return to physiologic pH.
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Tested Species: In-house tested species with positive results.
Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested.
Optimal dilutions should be determined by end users.
Type: Primary
Antigen: ASIC3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: near the N-terminus
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat