5-Fluorouracil ≥99% (by HPLC), powder, Sigma-Aldrich®
Supplier: SIGMA ALDRICH MICROSCOPY
5-Fluorouracil has been used to induce apoptosis in cells. It has been used as a chemosensitising agent. A potent antitumor agent that affects pyrimidine synthesis by inhibiting thymidylate synthetase, thus depleting intracellular dTTP pools. It is metabolized to ribonucleotides and deoxyribonucleotides, which can be incorporated into RNA and DNA. Treatment of cells with 5-FU leads to an accumulation of cells in S-phase and has been shown to induce p53 dependent apoptosis.
Expand 3 Items
5-Fluorouracil for synthesis, Sigma-Aldrich®
Supplier: Merck
5-Fluorouracil for synthesis, Sigma-Aldrich®
Expand 1 Items
5-Fluorouracil ≥99.0% (by HPLC, titration analysis)
Supplier: TCI
5-Fluorouracil ≥99.0% (by HPLC, titration analysis)
Expand 2 Items
5-Fluorouracil
Supplier: Apollo Scientific
This pyrimidine analogue, is an antineoplastic agent.
Expand 3 Items
5-Fluorouracil 99%
Supplier: Apollo Scientific
Antineoplastic agent. Not USP. Not for drug use.
Expand 2 Items
5-Fluorouracil, Millipore®
Supplier: Merck Millipore (Calbiochem)
5-Fluorouracil, Millipore®
Expand 1 Items
5-Fluorouracil ∼99%, powder
Supplier: MP Biomedicals
5-Fluorouracil (5-FU) inhibits the activity of thymidylate synthetase, which affects pyrimidine synthesis and leads to depletion of intracellular TTP pools.