Anti-STIL Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog # BOSSBS-9303R-HRP

Supplier: Bioss

Catalog # BOSSBS-9303R-HRP

Supplier: Bioss

Specifications

Antibody type:
Primary
Antigen name:
SCL/TAL1 interrupting locus
Antigen symbol:
STIL
Clonality:
Polyclonal
Conjugation:
HRP (Horseradish Peroxidase)
Host:
Rabbit
ImmunoChemistry:
Yes
Isotype:
IgG
Reactivity:
Human,
Rat,
Mouse
Western blot:
Yes
Cross adsorption:
No
Form:
liquid
Gene ID:
6491
Antigen synonyms:
MCPH7|SIL
Storage buffer:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% Gentamicin. Store at 4°C for 12 months.
Storage temperature:
Store at –20 °C for 12 months
Concentration:
1 μg/μl
Shipping temperature:
4°C
Purification:
Purified by Protein A
Pk:
100 µl

Specifications

About this item

TAL1 disruption at 1p32, a common rearrangement in the T-cell acute lymphoblastic leukemia, usually results in the formation of a SCL interrupting locus (SIL)-TAL1 fusion product. SIL is an immediate early gene whose expression is associated with cell proliferation. The Sil protein exhibits ubiquitous expression in hematopoietic cell lines and tissues. However, Sil protein levels remain tightly regulated during the cell cycle, achieving peak levels in mitosis and diminishing on transition to G1 phase. Overexpression of Sil in primary adenocarcinomas predicts metastatic spread, especially in lung tumors with increased mitotic activity.

Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500

Type: Primary
Antigen: STIL
Clonality: Polyclonal
Clone:
Conjugation: HRP (Horseradish Peroxidase)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat