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Anti-mTOR Thr2446 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Anti-mTOR Thr2446 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Katalog # BOSSBS-5331R-A680
Supplier:  Bioss
Anti-mTOR Thr2446 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Katalog # BOSSBS-5331R-A680
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    mTOR Thr2446
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 680
  • Flow cytometry:
    Yes
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Human,
    Mouse
  • Form:
    Liquid
  • Gene ID:
    1735
  • Antigen synonyms:
    FK506 binding protein 12 rapamycin associated protein 1|dJ576K7.1 FK506 binding protein 12 rapamycin associated protein 1|FK506-binding protein 12-rapamycin complex-associated protein 1|FRAP1|FLJ44809|Rapamycin and FKBP12 target 1|FK506 binding protein12-rapamycin associated protein 2|FKBP12-rapamycin complex-associated protein|FKBP rapamycin associated protein|Rapamycin target protein 1|mTOR|RAPT1|RAFT1|FKBP12 rapamycin complex associated protein|FRAP|Mammalian target of rapamycin|MTOR_HUMAN|Rapamycin target protein|OTTHUMP00000001983|Serine/threonine-protein kinase mTOR|Rapamycin associated protein FRAP2|FRAP2|FK506 binding protein12-rapamycin associated protein 1|FK506 binding protein 12 rapamycin associated protein 2|Mechanistic target of rapamycin|FK506 binding protein 12 rapamycin complex associated protein 1
  • Modification:
    Phosphorylation (Thr2446 )
  • Storage buffer:
    Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
  • Molecular weight:
    289 kDa
  • Storage temperature:
    Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic phosphopeptide derived from human mTOR around the phosphorylation site of Thr2446
  • Tested applications:
    ICC
  • Purification:
    Purified by Protein A
  • Pack type:
    Vial
  • Pk:
    100 µl

Specifications

About this item

mTOR is one of a family of proteins involved in cell cycle progression, DNA recombination, and DNA damage detection. In rat, it is a 289-kDa protein (symbolized RAFT1) with significant homology to the Saccharomyces cerevisiae protein TOR1 and has been shown to associate with the immunophilin FKBP12 in a rapamycin dependent fashion. The FKBP12-rapamycin complex is known to inhibit progression through the G1 cell cycle stage by interfering with mitogenic signaling pathways involved in G1 progression in several cell types, as well as in yeast. The binding of FRAP to FKBP12-rapamycin correlated with the ability of these ligands to inhibit cell cycle progression.

Type: Primary
Antigen: mTOR Thr2446
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range:
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse

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