Specifications
- Antibody type:Primary
- Antigen name:ACOT8
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Epitope:31-130/319
- Form:Liquid
- Gene ID:10005
- Antigen synonyms:acyl CoA thioesterase 8|Long chain fatty acyl CoA hydrolase|Acot8|Peroxisomal long-chain acyl-CoA thioesterase 1|ACOT8_HUMAN|PTE1|Acyl-coenzyme A thioesterase 8|HIV Nef associated acyl CoA thioesterase|Peroxisomal long chain acyl CoA thioesterase 1|Peroxisomal acyl-coenzyme A thioester hydrolase 1|Choloyl coenzyme A thioesterase|Thioesterase II|PTE-2|PTE 1|PTE2|PTE-1|Choloyl-coenzyme A thioesterase|PTE 2|Palmitoyl CoA hydrolase|Acyl-CoA thioesterase 8|Peroxisomal acyl CoA thioesterase 1|hACTE III|Peroxisomal acyl coenzyme A thioester hydrolase 1|HNAACTE|hACTE-III|HIV-Nef-associated acyl-CoA thioesterase|ACTEIII|hACTEIII|hTE
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:36 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human ACOT8
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
Acyl-CoA thioesterases are a group of enzymes that catalyse the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Acyl-coenzyme A Thioesterase 8, also known as ACOT8 may mediate Nef-induced down-regulation of CD4. It is a major thioesterase in peroxisomes and competes with BAAT (Bile acid CoA: amino acid N-acyltransferase) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). It shows a preference for medium-length fatty acyl-CoAs and may be involved in the metabolic regulation of peroxisome proliferation.
Type: Primary
Antigen: ACOT8
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 31-130/319
Host: Rabbit
Isotype: IgG
Reactivity: