Order Entry
Norway
ContactUsLinkComponent
Anti-FMR2/AFF2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Anti-FMR2/AFF2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-11703R-A750
Supplier:  Bioss
Anti-FMR2/AFF2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-11703R-A750
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    FMR2/AFF2
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 750
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Western blot:
    Yes
  • Epitope:
    1-80/1311
  • Form:
    Liquid
  • Antigen synonyms:
    AFF2|fragile X mental retardation 2|FRAXE|AF4/FMR2 family, member 2|FMR2|MRX2|Protein Ox19|OX19|mild or borderline mental retardation|fragile X mental retardation gene associated with FRAXE|Fragile X mental retardation 2 protein|AFF2_HUMAN|FMR2P|AF4/FMR2 family member 2|Protein FMR-2|Fragile X E mental retardation syndrome protein
  • Modification:
    Unmodified
  • Storage buffer:
    Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
  • Molecular weight:
    145 kDa
  • Storage temperature:
    Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic peptide derived from human AFF2
  • Tested applications:
    ICC
  • Purification:
    Purified by Protein A
  • Pack type:
    Vial
  • Pk:
    100 µl

Specifications

About this item

FMR2 is a 1311 amino acid nuclear protein belonging to the AF4 family. Expressed in the brain, placenta and lung, FMR2 exists as two isoforms produced by alternative splicing. Defects in the gene that encodes FMR2 have been found to be a cause of FRAXE, an X-linked form of mental retardation. Individuals expressing the FRAXE site also have more than two-hundred copies of a GCC repeat adjacent to CpG island, compared to six to thirty-five copies of the GCC repeat in a normal individual. It is believed that loss of FMR2 expression causes this GCC expansion of the FRAXE site.

Type: Primary
Antigen: FMR2/AFF2
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 1-80/1311
Host: Rabbit
Isotype: IgG
Reactivity: