652 Results for: "Shenandoah Biotechnology"

Supplier: Shenandoah Biotechnology

Activin A is a member of the transforming growth factor beta (TGF-β) family of proteins and functions to stimulate follicle-stimulat ing hormone (FSH) secretion. Activins are produced in many tissue types including the skin, gonads, lungs, and pitui 1 * 2 µG

Supplier: Shenandoah Biotechnology

Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF -A has several alternatively spliced isoforms, with VEGF-165 being the most abundant. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Growth hormone (GH) is an important mitogenic growth factor that is synthesized, stored, and secreted by somatotropic cells of the anterior pituitary gland. GH stimulates growth, cell reproduction, and cell regeneration. 1 * 1 mg

Supplier: Shenandoah Biotechnology

Growth regulated protein beta (GRO-beta), also known as CXCL2, is a chemokine that is secreted by macrophages, neutrophils, and mono cytes at sites of inflammation. GRO-beta functions as a chemoattractant for leukocytes and hematopoietic stem cells. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Monocyte chemotactic protein 2 (MCP-2), also known as CCL8, is a cytokine that is important during allergic and inflammatory respons es. MCP-2 activates mast cells, eosinophils, and basophils through the G protein-coupled chemokine receptors. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Fms-related tyrosine kinase 3 ligand (FLT-3 ligand) is a growth factor that regulates hematopoietic cell proliferation. FLT-3 ligan d signalling is transmitted through the fms-related tyrosine kinase 3 (FLT-3) receptor. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 2 (IL-2) is an immunomodulatory cytokine that is produced by lymphocytes.  IL-2 signals through the IL-2R receptor to in duce activated T cell proliferation and promote T cell differentiation. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Insulin-like growth factor I (IGF-I) is a growth factor that is produced by the liver. IGF-1 production is stimulated by growth hor mone (GH). IGF-I binds the insulin-like growth factor 1 receptor (IGF1R) and the insulin receptor. 1 * 1 mg

Supplier: Shenandoah Biotechnology

Interleukin 17E (IL-17E), also known as IL-25, is a member of the IL-17 family of cytokines. IL-17E binds to the IL-17BR receptor t o stimulate the secretion of the proinflammatory interleukin 8 (IL-8) chemokine. 1 * 1 mg

Supplier: Shenandoah Biotechnology

ANIMAL-FREE MOUSE SCF 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 3 is a cytokine that is produced by activated T cells and mast cells. IL-3 induces the differentiation of hematopoietic stem cells into myeloid precursor cells, such as erythrocyte, megakaryocyte, granulocyte, monocyte, and dendritic cell 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 22 (IL-22), also called IL-TIF, is an IL-10 family member that is produced by activated dendritic cells and T lymphocyte s. IL-22 signals via a heteroduplex receptor consisting of IL-22R and IL-10Rbeta chains. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 6 (IL-6) is a cytokine that is expressed by T cells, macrophages, and muscle cells. IL-6 acts to stimulate an immune re sponse upon infection or trauma. IL-6 has both pro-inflammatory and anti-inflammatory functions. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Receptor activator of nuclear factor kappa-B Ligand (RANKL) is a cell-bound marker related to the tumor necrosis factor (TNF) family of proteins. RANKL plays a critical role in bone metabolism and osteoclast differentiation. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Receptor activator of nuclear factor kappa-B Ligand (RANKL) is a cell-bound marker related to the tumor necrosis factor (TNF) family of proteins. RANKL plays a critical role in bone metabolism and osteoclast differentiation. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 7 (IL-7) is a hematopoietic cytokine that is an important regulator of B and T cell development. IL-7 is secreted by bo ne marrow and thymic stromal cells, dendritic cells, intestinal epithelial cells, hepatocytes, and keratinocytes. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Fibroblast growth factor 7 (FGF7), also known as keratinocyte growth factor (KGF), is a potent mitogen that regulates epithelial cel l migration and differentiation. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Stromal cell-derived factor-1 alpha (SDF-1α), also called CXCL12a, is one of two SDF-1 splice variants made by a wide variety of cel ls upon stimulation by inflammatory cytokines such as tumor necrosis factors , interleukin 1 , and lipopolysaccharide 1 * 2 µG

Supplier: Shenandoah Biotechnology

Fibroblast growth factor 9 (FGF9) is a mitogen and survival factor for nerve and mesenchymal cells. FGF9 functions as an autocrine and paracrine factor to support the growth and survival of motor neurons and prostate tissue. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Leptin is a hormone that is produced by adipose tissue and plays critical roles in the physiologic regulation of body weight. Lepti n acts through the leptin receptor (LEPR) to regulate adipose mass by inhibiting hunger and balancing energy usage. 1 * 5 µG

Supplier: Shenandoah Biotechnology

Interleukin 15 (IL-15) is a widely expressed proinflammatory cytokine that is structurally and functionally related to interleukin 2 (IL-2). IL-15 signals through JAK kinases to activate STAT3, STAT5, and STAT6 transcription factors. 1 * 1 mg

Supplier: Shenandoah Biotechnology

Interleukin 15 (IL-15) is a widely expressed proinflammatory cytokine that is structurally and functionally related to interleukin 2 (IL-2). IL-15 signals through JAK kinases to activate STAT3, STAT5, and STAT6 transcription factors. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 1 alpha (IL-1α) is expressed by epithelial cells, activated macrophages, neutrophils, and endothelial cells to regulate immune responses. I 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 1 beta (IL-1β) is a pro-inflammatory cytokine that is produced by monocytes, macrophages, and dendritic cells (DCs). 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 11 (IL-11) is a member of the gp130 family of cytokines. IL-11 functions to promote hematopoietic stem cell proliferati on and megakaryocyte differentiation. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 9 (IL-9) is a cytokine produced by type 2 T helper (Th2) cells and regulates hematopoietic cells. IL-9 signals through the interleukin 9 receptor (IL9R) to activate STAT signaling. 1 * 500 µG

Supplier: Shenandoah Biotechnology

Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-a, TGF-b and EGF signaling. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Oncostatin M (OSM) is a cytokine that is produced by macrophages, dendritic cells, and T lymphocytes during inflammatory events. Th e Type-I and Type-II OSM receptors are located on the cell surface of endothelial and tumor cells. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Acidic fibroblast growth factor (aFGF), also known as FGF1, is a potent inducer of DNA synthesis, cell proliferation, and has chemot actic activities. aFGF regulates cardiogenesis through protein kinase C signaling. 1 * 500 µG