117412 Results for: "Rhod-FF+AM&pageNo=9"

Potent cell permeable and metabolically stable specific inhibitor of hSIRT1 (IC50=98nM in vivo / IC50=38nM in vitro; compared to hSIRT2: IC50=19µM and hSIRT3: IC50=48µM) with no effect on human histone deacetylases (HDACs) class I and class II, nor NAD glycohydrolase (IC50>100µg). Inhibits the deacetylation of p53 (IC50=1µM).

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BAY 61-3606 hydrochloride ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Syk inhibitor

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RO-3306 ≥95% (by 1H-NMR)

Supplier: Enzo Life Sciences

CDK/cyclin inhibitor

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FK-866 ≥98% (by NMR)

Supplier: Enzo Life Sciences

Nampt inhibitor

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Cylindrospermopsin ≥95% (by HPLC)

Supplier: Enzo Life Sciences

Protein synthesis inhibitor

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Gramicidin A (from Bacillus brevis) ≥90% (by HPLC)

Supplier: Enzo Life Sciences

Ionophore antibiotic.

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Butein ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Tyrosine kinase inhibitor

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Xanthohumol ≥98% (by HPLC)

Supplier: Enzo Life Sciences

DGAT inhibitor

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Isoxanthohumol ≥98% (by 1H-NMR)

Supplier: Enzo Life Sciences

Phytoestrogen.

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Evodiamine ≥98% (by HPLC)

Supplier: Enzo Life Sciences

TRPV1 antagonist

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Baccatine III ≥95% (by HPLC)

Supplier: Enzo Life Sciences

Antitumor agent.

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Hispolon ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Apoptosis inducer.

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5Z-7-Oxozeaenol (from Deuteromycetes sp.) ≥95% (by HPLC)

Supplier: Enzo Life Sciences

Inhibitor of the JNK/p38 pathways. Inhibits anisomycin-induced but not TNF-induced JNK/p38 activation. Potent protein kinase inhibitor
>A naturally isolated cell-permeable fungal resorcylic lactone that acts as a selective and highly potent inhibitor against the MAPKKK TAK1 activity (IC50 = 8nM) in an ATP-competitive and irreversible manner; also inhibits MEK1 (IC50 = 411nM) and three other MAPKKKs (IC50 ≥268 nM against MEKK1, ASK1, and MEKK4) but at much higher concentrations. Shown to inhibit IL-1-induced/TAK1-mediated, but not H2O2-induced/TAK1-independent, JNK and p38 phosphorylation in 293 cells.

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Nadifloxacin ≥98%

Supplier: Enzo Life Sciences

Fluoroquinolone with broad spectrum activity against Gram-negative and Gram-positive bacteria. Inhibits the generation of O^2- and OH radicals by neutrophils. Inhibits the production of inflammatory cytokines.

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Enniatin A (from Fusarium sp.) ≥97% (by HPLC)

Supplier: Enzo Life Sciences

White to off-white crystalline solid

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Sparfloxacin ≥98%

Supplier: Enzo Life Sciences

Fluoroquinolone with broad spectrum antibacterial activity against Gram-positive and Gram-negative bacteria. Inhibits bacterial DNA gyrase (topoisomerase). Effective against Mycobacterium tuberculosis. Shows photosensitizing effects.