42864 Results for: "ProSci Inc."

Supplier: ProSci Inc.

The UCHT2 monoclonal antibody specifically reacts with human CD5, a 67 kDa type 1 transmembrane glycoprotein. CD5 is expressed on mature T cells, a subset of B cells, and peripheral blood dendritic cells. B cells that are CD5+ produce mostly IgM polyreactive antibodies. Its ligand is CD72, which is involved in T, B cell proliferation and interaction. The UCT2 antibody also recognizes non-human primate CD5.

Supplier: ProSci Inc.

The O323 monoclonal antibody specifically binds to the human CD27, which is a lymphocyte-specific member of the TNF/NGF-R family, expressed on a subset of human thymocytes and the majority of the mature T cells. CD27 is upregulated by T lymphocytes stimulation, and binds to CD70, enhancing the interaction between T and B lymphocytes. CD27 is a memory marker of B cells.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100. For FACS starting dilution is: 1:10~50.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100. For FACS starting dilution is: 1:10~50.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

The BM8.1 monoclonal antibody specifically binds to the Mouse125 kDa F4/80 antigen, expressed by most mature macrophages. F4/80 is a transmembrane protein used as a marker of macrophages, although it is also expressed on Kupffer and Langerhans cells. The expression of F4/80 antigen is upregulated on bone marrow cells stimulated in vitro with the macrophage colony stimulating factor. The F4/80 antigen is a requirement for the induction of CD8 T cells-mediated peripheral tolerance.

Supplier: ProSci Inc.

The BM8.1 monoclonal antibody specifically binds to the Mouse125 kDa F4/80 antigen, expressed by most mature macrophages. F4/80 is a transmembrane protein used as a marker of macrophages, although it is also expressed on Kupffer and Langerhans cells. The expression of F4/80 antigen is upregulated on bone marrow cells stimulated in vitro with the macrophage colony stimulating factor. The F4/80 antigen is a requirement for the induction of CD8 T cells-mediated peripheral tolerance.

Supplier: ProSci Inc.

The BM8.1 monoclonal antibody specifically binds to the Mouse125 kDa F4/80 antigen, expressed by most mature macrophages. F4/80 is a transmembrane protein used as a marker of macrophages, although it is also expressed on Kupffer and Langerhans cells. The expression of F4/80 antigen is upregulated on bone marrow cells stimulated in vitro with the macrophage colony stimulating factor. The F4/80 antigen is a requirement for the induction of CD8 T cells-mediated peripheral tolerance.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

The 5E10 monoclonal antibody specifically reacts with human CD90, also known as thymus cell antigen-1 (Thy-1). CD90 is a 25 to 37 kDa GPI-anchored protein is the smallest member of the Ig superfamily. CD90 is expressed on thymocytes, neurons, mesenchymal stem cells, hematopoietic stem cells, NK cells, and follicular dendritic cells and plays a role in inflammation, metastasis, apoptosis, and nerve regeneration. The 5E10 antibody can be used for the enriching high proliferative potential colony-forming cells (HIPP-CFC).

Supplier: ProSci Inc.

The AK-4 monoclonal antibody specifically reacts with human CD62P (P-Selectin), a 140 kDa type I transmembrane glycoprotein also known as platelet activation-dependent granule membrane protein (PADGEM). Upon activation it is quickly transported to the plasma membrane from the alpha-granules of platelets and WEibel-Palade bodies of endothelial cells. It is essential to the functions of cell adhesion during inflammatory reactions and in the interaction of platelets with monocytes and neutrophils.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

The HM40-3 monoclonal antibody reacts with mouse CD40, a 48 kDa type I glycoprotein known as Bp50. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The HM40-3 antibody blocks the binding of CD40L (CD154) and stimulates B and dendritic cell proliferation.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

The 5C3 monoclonal antibody specifically reacts with human CD40, a 48 kDa type I glycoprotein. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The 5C3 antibody partially blocks the binding of CD40L (CD154). In the presence of IL-4 or PMA, the 5C3 antibody promotes B cell proliferation.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

The 16-10A1 antibody reacts with mouse CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 also binds a second B7 ligand known as CD86 (B7-2). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction/co-stimulatory signaling between the B7 ligands and CD28 or CTLA-4 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.

Supplier: ProSci Inc.

For WB starting dilution is: 1:1000.