VWR® IS High Capacity Balances
Supplier: VWR Collection
The IS range of high capacity balances are robust, reliable and ensure high performance. Models are equipped with either a backlit LCD with adjustable contrast, a large graphic display or a large 5" colour touch screen, the balances have been designed to deliver top performance at competitive prices.
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Funnel with ball and lid, electrostatic conductive, ARNOLD, V2.0
Supplier: S.C.A.T.
The strong and electrically conductive safety funnel 'ARNOLD' V2.0 with lid and ball meets the highest requirements for safe disposal of hazardous liquid waste due to its combination of two independent safety mechanisms. The two safety features consist of a ball integrated in the funnel basin and a sealing ring incorporated in the hinged lid of the funnel, which prevent the escape of toxic gases. The funnel is especially designed for explosive or flammable substances, as the PE-HD material used is eclectically conductive and charges can be dissipated via the ground cable.
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Anti-KIF14 Rabbit Polyclonal Antibody (Alexa Fluor® 555)
Supplier: Bioss
Microtubule motor protein that binds to microtubules with high affinity through each tubulin heterodimer and has an ATPase activity (By similarity). Plays a role in many processes like cell division, cytokinesis and also in cell proliferation and apoptosis (PubMed:24784001, PubMed:16648480). During cytokinesis, targets to central spindle and midbody through its interaction with PRC1 and CIT respectively (PubMed:16431929). Regulates cell growth through regulation of cell cycle progression and cytokinesis (PubMed:24854087). During cell cycle progression acts through SCF-dependent proteasomal ubiquitin-dependent protein catabolic process which controls CDKN1B degradation, resulting in positive regulation of cyclins, including CCNE1, CCND1 and CCNB1 (PubMed:24854087). During late neurogenesis, regulates the cerebellar, cerebral cortex and olfactory bulb development through regulation of apoptosis, cell proliferation and cell division (By similarity). Also is required for chromosome congression and alignment during mitotic cell cycle process (PubMed:15843429). Regulates cell spreading, focal adhesion dynamics, and cell migration through its interaction with RADIL resulting in regulation of RAP1A-mediated inside-out integrin activation by tethering RADIL on microtubules (PubMed:23209302).
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Anti-GRB10/GRB14 Rabbit Polyclonal Antibody (Alexa Fluor® 488)
Supplier: Bioss
Adapter protein which modulates coupling of a number of cell surface receptor kinases with specific signaling pathways. Binds to, and suppress signals from, activated receptors tyrosine kinases, including the insulin (INSR) and insulin-like growth factor (IGF1R) receptors. The inhibitory effect can be achieved by 2 mechanisms: interference with the signaling pathway and increased receptor degradation. Delays and reduces AKT1 phosphorylation in response to insulin stimulation. Blocks association between INSR and IRS1 and IRS2 and prevents insulin-stimulated IRS1 and IRS2 tyrosine phosphorylation. Recruits NEDD4 to IGF1R, leading to IGF1R ubiquitination, increased internalization and degradation by both the proteasomal and lysosomal pathways. May play a role in mediating insulin-stimulated ubiquitination of INSR, leading to proteasomal degradation. Negatively regulates Wnt signaling by interacting with LRP6 intracellular portion and interfering with the binding of AXIN1 to LRP6. Positive regulator of the KDR/VEGFR-2 signaling pathway. May inhibit NEDD4-mediated degradation of KDR/VEGFR-2. GRB14 is a potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.
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Anti-GRB10/GRB14 Rabbit Polyclonal Antibody (Alexa Fluor® 647)
Supplier: Bioss
Adapter protein which modulates coupling of a number of cell surface receptor kinases with specific signaling pathways. Binds to, and suppress signals from, activated receptors tyrosine kinases, including the insulin (INSR) and insulin-like growth factor (IGF1R) receptors. The inhibitory effect can be achieved by 2 mechanisms: interference with the signaling pathway and increased receptor degradation. Delays and reduces AKT1 phosphorylation in response to insulin stimulation. Blocks association between INSR and IRS1 and IRS2 and prevents insulin-stimulated IRS1 and IRS2 tyrosine phosphorylation. Recruits NEDD4 to IGF1R, leading to IGF1R ubiquitination, increased internalization and degradation by both the proteasomal and lysosomal pathways. May play a role in mediating insulin-stimulated ubiquitination of INSR, leading to proteasomal degradation. Negatively regulates Wnt signaling by interacting with LRP6 intracellular portion and interfering with the binding of AXIN1 to LRP6. Positive regulator of the KDR/VEGFR-2 signaling pathway. May inhibit NEDD4-mediated degradation of KDR/VEGFR-2. GRB14 is a potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.
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Anti-GRB10/GRB14 Rabbit Polyclonal Antibody (Cy7®)
Supplier: Bioss
Adapter protein which modulates coupling of a number of cell surface receptor kinases with specific signaling pathways. Binds to, and suppress signals from, activated receptors tyrosine kinases, including the insulin (INSR) and insulin-like growth factor (IGF1R) receptors. The inhibitory effect can be achieved by 2 mechanisms: interference with the signaling pathway and increased receptor degradation. Delays and reduces AKT1 phosphorylation in response to insulin stimulation. Blocks association between INSR and IRS1 and IRS2 and prevents insulin-stimulated IRS1 and IRS2 tyrosine phosphorylation. Recruits NEDD4 to IGF1R, leading to IGF1R ubiquitination, increased internalization and degradation by both the proteasomal and lysosomal pathways. May play a role in mediating insulin-stimulated ubiquitination of INSR, leading to proteasomal degradation. Negatively regulates Wnt signaling by interacting with LRP6 intracellular portion and interfering with the binding of AXIN1 to LRP6. Positive regulator of the KDR/VEGFR-2 signaling pathway. May inhibit NEDD4-mediated degradation of KDR/VEGFR-2. GRB14 is a potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.
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Finntip™ Filtered Pipette Tips
Supplier: Thermo Fisher Scientific
Integral filter made from water-repellent PE which does not swell on accidental penetration by liquid, allowing recovery of the sample. Protect pipettes and the samples from contamination with Thermo Scientific™ Finntip™ Filtered Pipette Tips. These sterile, disposable pipette tips keep pipettes clean, and are perfect for PCR amplification applications and for pipetting radioactive, infectious, and aerosol-emitting samples. Available in racks with a wide volume range of 0,2 μl to 10 ml.
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VWR® Hitachi Chromaster Plus HPLC System
Supplier: VWR Collection
Experience the next level of high-performance liquid chromatography with the Chromaster Plus HPLC system. This latest version boasts a sleek new design and enhanced performance features, including the upgraded CM5310 column oven and CM5410 UV detector. The new design offers a modern and user-friendly interface, while the enhanced performance of the CM5310 column oven and CM5410 UV detector ensures superior results. Additionally, users can enjoy peace of mind with an extended warranty coverage.
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High-capacity toploading laboratory balances, Cubis® II MCE
Supplier: Sartorius Balances
Cubis® II MCE high-capacity toploading balances with essential user interface offer a maximum load between 11,2 and 70,2 kg and readability between 0,1 and 1 g provide the ideal model for every application.
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Analytical laboratory balances, Cubis® II MCE
Supplier: Sartorius Balances
Cubis® II MCE analytical balances with essential user interface offer a maximum weighing capacity between 120 and 520 g in combination with readability of 0.1 mg.
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J.T.Baker®, Robotic Tips Type TE
Supplier: Avantor
Suitable for use on Tecan Freedom EVO or Tecan Fluent. Available in conductive and non conductive versions, with or without filter, and in CE-IVD marked version for clinical diagnostic applications.
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Eco Hi-Vis T-Shirts, Short Sleeve
Supplier: Portwest
Hi-Vis T-Shirt made from 100% recycled polyester fabric.
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Cleanroom gloves, polychloroprene, DermaShield® 73-711 / 73-721
Supplier: Ansell
Hand-specific, ergonomically designed gloves with a beaded cuff. Ideal for use in laboratories, pharmaceutical, biotech and medical device manufacturing.
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Rotary sample changer 7200 - for piston burettes and automatic titrators
Supplier: SI Analytics
The number of samples to be processed is growing constantly while at the same time the demands on reliability are increasing in accordance with GLP and ISO standards. The SI Analytics sample changer (TW 7200) helps you meet these increased requirements and free up highly qualified employees from routine work. TW 7200 basic unit with two integrated magnetic stirrers, including external power supply 100 to 240 V with adapters for EU, US and UK, USB cable for direct PC connection and connection cable for rod stirrer.
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Jackets, Portwest Texo, TX10
Supplier: Portwest
This hardwearing contrast colour jacket is made of 60% cotton and 40% polyester. The soft handle cotton rich fabric is built to last and will look and feel great. Cotton ensures it washes well at 60 °C whilst the polyester gives a ruggedness essential for daily use.
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Industrial overalls, AlphaTec® 2000 STANDARD
Supplier: Ansell
These overalls consisting of two layers of fabric (non woven inner layer and microporous PE film) provide both protection and comfort with exceptional liquid and particulate protection. Ideal for industrial applications.
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Winter Jackets, PW2
Supplier: Portwest
Stylish, functional, and durable, the PW2 winter jacket offers protection and warmth in extreme weather conditions. Key features include contrast coloured panels for added style, an adjustable detachable hood, and plenty of pockets for storage.
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Pierce™ Protein Concentrators
Supplier: Thermo Fisher Scientific
Protein Concentrators PES are disposable ultrafiltration centrifugal devices with a polyethersulfone (PES) membrane for concentration, desalting, and buffer exchange of biological samples such as proteins and nucleic acids.
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HPLC columns, LiChrospher®
Supplier: Merck
LiChrospher® is Merck's reliable and versatile, traditionally-produced, spherical silica. LiChrospher® is available with different modifications.
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Corning® Matrigel® Basement Membrane Matrix, Corning
Supplier: Corning
Growth Factor Reduced (GFR) formulation is well suited for applications that require a more highly defined basement membrane preparation.
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Cell culture flasks, Nunc™
Supplier: Thermo Fisher Scientific
These Nunc™ cell culture flasks are designed for culture consistency, cell health, and reproducibility. Choose from a variety of surfaces and sizes with culture areas ranging from 25 to 500 cm² to suit your specific applications and cell types.
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Electronic overhead stirrers, Hei-TORQUE series
Supplier: Heidolph Instruments GmbH & Co.KG
Powerful electronic stirrers that feature a smooth start operation which prevents spills and splashing media. The speed ramps up slowly until set speed has been reached. Both models feature safe start and stop of operation via an intuitive glass slide touch panel to avoid accidental start-up. An overtemperature sensor shuts off the unit in dangerous heat-up situations, ideal for unattended continuous operation. All units are designed for continuous 24-hour operation, including challenging high viscosity applications in polymer research. High torque levels give better mixing results in less time, maintenance-free motors reduce repairs and down time. Hei-TORQUE Value 400 and Hei-TORQUE Precision 400 units have two speed gears.
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Cryofuge™ 8/16 Blood Banking Centrifuges with GreenCool Technology
Supplier: Thermo Scientific
Thermo Scientific™ Cryofuge™ 8/16 Blood Banking Centrifuges with GreenCool Technology bring enhanced sustainability to blood processing centres. Featuring a natural refrigerant (CO2) cooling system, they offer reduced energy consumption and heat output, have short cool-down times and maintain excellent temperature stability for precise results whilst complying with global standards.
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Nunc-Immuno™ modules
Supplier: Thermo Fisher Scientific
PS. Nunc-Immuno™ modules have been developed for ELISA techniques where the demands of versatility require a different solution to the standard 96-well plate format. Available with a choice of MaxiSorp™, PolySorp™, MediSorp™ and MultiSorp™ surfaces. All MaxiSorp™ modules are certified for binding homogeneity. Framed modules (external dimensions: 128×86 mm) fit all standard equipment.
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HPLC columns, Accucore™ XL C18 and XL C8
Supplier: Thermo Fisher Scientific
Based on Core Enhanced Technology, using 4 µm solid core particles, these columns allow users of conventional HPLC methods to enjoy performance far beyond that of columns packed with 5, 4 or even 3 μm fully porous particles. Very high separation efficiencies, using standard HPLC instruments and conditions, provide increased peak resolution and lower limits of detection. An ultra-stable packed bed results in exceptionally robust columns that demonstrate excellent retention and response reproducibility.
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UV/Vis Calibration Standards
Supplier: HELLMA
The Hellma® calibration standards comply with all necessary standards and regulations and thus offer the highest quality for recalibrating your spectrometer.
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BinLiners™ and BinLiner™ Stands
Supplier: MICRONOVA
LDPE Micronova BinLiners™ are ideal for the collection and disposal of waste, collection and transportation of parts or raw materials, and storage in cleanrooms and controlled environments. Thickness of 1 to 6 mm available for a variety of applications; including covering equipment, holding production waste, document storage, lining large production totes and so on.
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Industrial scales, modular, Ranger 7000
Supplier: OHAUS
The Ranger 7000 series are rugged, high performance industrial scales for the toughest jobs. Ten advanced application modes can provide results for complex applications while minimising manual calculations. Ranger 7000 will meet a variety of industrial applications from recipes formulation through automatic filling systems to density weighing of concrete. The scales have a bright backlit display and navigation panel that is comprised of a keypad with 5 quick, 8 function, and 12 alphanumeric keys and a 109 mm graphic display, which can be operated in multiple languages.
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Portable balances, Scout® SKX series
Supplier: OHAUS
The Scout® SKX series has been designed for education applications. The overload protection and large backlit LCD, backed by education software makes the Scout® the ideal balance for the classroom. The integrated transportation lock protects the load cell from damage during stacking storage and transportation. Can be used either in battery-powered mode (4× AA batteries, not included) or via the AC adapter, with power saving auto shut-off function and low battery indicator. The SKX123 has an ingenious draught shield with an easy to remove top cover piece.
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Human EXTL2 ELISA Kit
Supplier: Antibodies.com
Human EXTL2 ELISA Kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human EXTL2 in serum, plasma, tissue homogenates, and other biological fluids.