158765 Results for: "ICRF-193&pageNo=12"

This antibody is specific to a conserved determinant of the p53 protein. PAb 122 binds to the C-terminus (aa 370-378) of both wild type and mutated p53. When microinjected into nuclei, PAb 122 blocked re-entry into the S-phase of the cell cycle. Mutation and/or allelic loss of p53 is one of the causes of a variety of mesenchymal and epithelial tumors. If it occurs in the germ line, such tumors run in families. p53 binds to a DNA consensus sequence, the p53 response element, and it regulates normal cell growth cycle events by activating transcription of genes, involved either in progression through the cycle, or causing arrest in G1 when the genome is damaged. In most transformed and tumor cells the concentration of p53 is increased 5-1000 fold over the minute concentrations (1000 molecules cell) in normal cells, principally due to the increased half-life (4 h) compared to that of the wild-type (20 min). The protein in the nucleus, but is detectable at the plasma membrane during mitosis and when certain mutations modulate cytoplasmic/nuclear distribution. Its the most commonly mutated gene in spontaneously occurring human cancers. Mutations arise with an average frequency of 70% but incidence varies from zero in carcinoid lung tumors to 97% in primary melanomas. High concentrations of p53 protein are transiently expressed in human epidermis and superficial dermal fibroblasts following mild ultraviolet irradiation.

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C16 dihydro Ceramide-d9 (d18:0/16:0-d9), solid

Supplier: Cayman Chemical

C16 dihydro Ceramide-d9 (d18:0/16:0-d9), solid

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Anti-Cadherin 16 Rabbit Monoclonal Antibody [clone: ARC2212]

Supplier: ANTIBODIES.COM

Rabbit monoclonal [ARC2212] antibody to Cadherin 16 for WB and ICC/IF with samples derived from Human and Mouse.

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Anti-Cytokeratin 13 Rabbit Monoclonal Antibody [clone: ARC1824]

Supplier: ANTIBODIES.COM

Rabbit monoclonal [ARC1824] antibody to Cytokeratin 13 for WB, IHC and ICC/IF with samples derived from Human, Mouse and Rat.

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Anti-IL-12B Rabbit Monoclonal Antibody [clone: ARC60328]

Supplier: ANTIBODIES.COM

Rabbit monoclonal [ARC60328] antibody to IL-12B for WB with samples derived from human.

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Anti-Ankyrin B Mouse Monoclonal Antibody [Clone: S105-13]

Supplier: ANTIBODIES.COM

Mouse monoclonal [S105-13] antibody to Ankyrin B for WB, IHC and ICC/IF with samples derived from human, mouse and rat.

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Anti-15 Lipoxygenase 1 Mouse Monoclonal Antibody [clone: OTI7H6]

Supplier: ANTIBODIES.COM

Anti-15 Lipoxygenase 1 Mouse Monoclonal Antibody [clone: OTI7H6]

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Anti-15 Lipoxygenase 1 Mouse Monoclonal Antibody [clone: OTI3G8]

Supplier: ANTIBODIES.COM

Anti-15 Lipoxygenase 1 Mouse Monoclonal Antibody [clone: OTI3G8]

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Anti-15 Lipoxygenase 1 Mouse Monoclonal Antibody [clone: OTI7H6]

Supplier: ANTIBODIES.COM

Anti-15 Lipoxygenase 1 Mouse Monoclonal Antibody [clone: OTI7H6]

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Anti-Transferrin Mouse Monoclonal Antibody [Clone: HTF-14]

Supplier: ANTIBODIES.COM

Mouse monoclonal [HTF-14] antibody to Transferrin for WB, IHC-P, ICC, ELISA, RIA and functional studies with samples derived from human, rabbit and porcine.

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Anti-Transferrin Mouse Monoclonal Antibody [Clone: HTF-14]

Supplier: ANTIBODIES.COM

Mouse monoclonal [HTF-14] antibody to Transferrin for WB, IHC-P, ICC, ELISA, RIA and functional studies with samples derived from human, rabbit and porcine.

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Anti-CD161 Mouse Monoclonal Antibody [Clone: 10/78]

Supplier: ANTIBODIES.COM

Mouse monoclonal [10/78] antibody to CD161 for flow cytometry, IP, WB, IHC-Fr and RIA with samples derived from rat.

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Anti-CD45RB Mouse Monoclonal Antibody [clone: BRA-11]

Supplier: ANTIBODIES.COM

Mouse monoclonal [BRA-11] antibody to CD45RB for flow cytometry, IF, WB and IHC-P with samples derived from human.

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Organic reference standard, (S)-(-)-Nicotine 10 µg/ml in methanol

Supplier: LGC Standards PROMOCHEM

Organic Standard, (S)-(-)-Nicotine 10 µg/ml in methanol, Pack type: Glass bottle

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Power supply, switching, regulated, 24 V, 12,5 A, ALF2412 / 300 W

Supplier: ELC

Power supply, Fixed power supply, switching, regulated, 24 V, 12,5 A at 24 V

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Anti-CD99 Mouse Monoclonal Antibody [clone: HO36-1.1]

Supplier: ANTIBODIES.COM

Mouse monoclonal [HO36-1.1] antibody to CD99 for Flow Cytometry, IF and IHC-P with samples derived from Human and Rat.

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Anti-CD34 Mouse Monoclonal Antibody [clone: QBEnd/10]

Supplier: ANTIBODIES.COM

Mouse monoclonal [QBEnd/10] antibody to CD34 for Flow Cytometry, IF and IHC-P with samples derived from human, cynomolgus monkey and rhesus monkey.

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Anti-I-Ek Mouse Monoclonal Antibody [clone: 14-4-4S]

Supplier: Abnova

Mouse monoclonal antibody raised against native I-Ek.

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Anti-C-peptide Mouse Monoclonal Antibody [clone: CII-11]

Supplier: Abnova

Mouse monoclonal antibody raised against synthetic peptide of C-peptide.

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Sodium chloride 1.0 M NaCl (1.0N) volumetric solution, Fluka™

Supplier: Honeywell Chemicals

Sodium chloride 1.0 M NaCl (1.0N) volumetric solution, Fluka™

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MA VPH matrix spike mix with surrogate (14 components)

Supplier: Restek

The MA VPH matrix spike mix consists of 14 components they are (C5) n-pentane, (C9) n-nonane, benzene, 2,5-dibromotoluene (SS), ethylbenzene, 2-methylpentane, methyl tert-butyl ether (mtbe), naphthalene, toluene, 1,2,4-trimethylbenzene, 2,2,4-trimethylpentane (isooctane), m-xylene, o-xylene and p-xylene.