Supplier: Bioss

Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.

Supplier: VWR Collection

Diepvriesrekken als opslag- en voorraadsysteem voor staande ULT-vriezers maken het organiseren van uw monsters eenvoudiger.

Supplier: VWR Collection

ND13-flacons met schroefhals zijn vervaardigd uit borosilicaatglas van de eerste hydrolytische klasse met vlakke bodem. Ze kunnen worden gekocht met een verscheidenheid aan polypropyleen afdichtingsstijlen en septa-materialen.

Supplier: VWR Collection

Deze vacuümfiltratie-apparaten zijn zeer nuttig bij monsterscheiding en -zuivering in grote hoeveelheden.

Supplier: Avantor

BAKERBOND® Q2100 LC phases have been specially designed to solve the challenges of most routine samples. They can also be a good starting point for new method development projects. With options of four widely used chemistries and three particle sizes BAKERBOND® Q2100 can be a useful addition to your analytical toolkit.

Supplier: Retsch GmbH

Sieves made from 304 stainless steel are individually laser engraved with clear and precise labelling for full traceability. They are fully compatible with Retsch's existing products and can be combined with other sieves without problems.

Supplier: Restek

Highly base-deactivated spherical silica manufactured by Restek. Pinnacle® DB Phenyl columns offer alternate selectivity to straight chain hydrocarbon phases, especially for aromatic analytes. Replaces Hypersil® BDS Phenyl and Pinnacle® Phenyl Amine.

Supplier: Restek

Inlet liners with deactivation improve trace-level analysis that are suitable for agilent GCs equipped with split/splitless inlets. It is made of borosilicate glass.

Supplier: ProSci Inc.

Anti-CLTA Goat Polyclonal Antibody

Supplier: Lovibond

A wide range of test discs containing a series of graded glass filters, which have been pre-calibrated to give direct test readings. The unique feature of Lovibond® test discs is that they incorporate coloured glass filters which are colour stable and not affected by UV light or extreme environmental conditions.

Supplier: Bioss

This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.

Supplier: Bioss

Inhibits GTP exchange on Ran. Forms a Ran-GTP-RANBP1 trimeric complex. Increase GTP hydrolysis induced by the Ran GTPase activating protein RANGAP1. May act in an intracellular signaling pathway which may control the progression through the cell cycle by regulating the transport of protein and nucleic acids across the nuclear membrane.

Supplier: Bioss

FOXB1 and FOXB2 are winged helix/forkhead transcription factors. FOXB1 is specifically expressed in the developing central nervous system (CNS). Early embryonic FOXB1 expression is restricted to the mammiliary body region of the caudal hypothalamus, midbrain, hindbrain and spinal cord. FOXB1 may play a role in postnatal growth, lactation and CNS development.

Supplier: Bioss

The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

Supplier: Bioss

Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity (By similarity). Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome.

Supplier: Bioss

FOXB1 and FOXB2 are winged helix/forkhead transcription factors. FOXB1 is specifically expressed in the developing central nervous system (CNS). Early embryonic FOXB1 expression is restricted to the mammiliary body region of the caudal hypothalamus, midbrain, hindbrain and spinal cord. FOXB1 may play a role in postnatal growth, lactation and CNS development.

Supplier: Bioss

Calcium-dependent cell-adhesion protein (By similarity). May play a role in activity-induced synaptic reorganization underlying long term memory (By similarity). Could be involved in CDH2 internalisation through TAOK2/p38 MAPK pathway. In hippocampal neurons, may play a role in the down-regulation of dendritic spines, maybe through its action on CDH2 endocytosis (By similarity).

Supplier: Bioss

SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. Required for maintenance of ER network. Implicated in the suppression of cell death.Tissue specificity: Isoform 1 is highly expressed in heart, brain, liver skeletal muscle and pancreas. Isoform 3 is moderately expressed in placenta, lung and kidney. Isoform 4 is highly expressed in testis and small intestine.

Supplier: Bioss

Inhibits GTP exchange on Ran. Forms a Ran-GTP-RANBP1 trimeric complex. Increase GTP hydrolysis induced by the Ran GTPase activating protein RANGAP1. May act in an intracellular signaling pathway which may control the progression through the cell cycle by regulating the transport of protein and nucleic acids across the nuclear membrane.

Supplier: Bioss

Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

Supplier: Bioss

The RAS oncogene (MIM 190020) is mutated in nearly one-third of all human cancers. Members of the RAS superfamily are plasma membrane GTP-binding proteins that modulate intracellular signal transduction pathways. A subfamily of RAS effectors, including RASSF3, share a RAS association (RA) domain.[supplied by OMIM, Jul 2003].

Supplier: Bioss

Increases ligand-dependent transcriptional activity of AR and promotes AR sumoylation. The stimulation of AR activity is dependent upon sumoylation.Tissue specificity:Expressed most abundantly in ovary and, at lower levels, in prostate, spleen and testis. Weak expression, if any, in thymus, small intestine, colon and peripheral blood leukocytes.

Supplier: Merck

Ascentis® Express 90 Å Phenyl-Hexyl high-speed, high-performance liquid chromatography columns are based on a Fused-Core® particle design.

Supplier: HUBER

Chiller with air-cooled refrigerating unit and circulation pump. Evaporator (cooler), tank and housing of stainless steel. Pressure-suction pump made of industrial plastic material. Digital Temperature adjustment and digital temperature display. Level indicator with sight glass.

Supplier: VARIAN

These hydrophilic polymers are suitable for both aqueous SEC and organic GPC using the majority of polar organic solvents. The two types are chemically similar that can be used together across a wider molecular weight range with aqueous and organic polymers.

Supplier: HAMMERBACHER

Carcass construction, i.e. each cabinet can stand alone. Carcass glued.

Supplier: VWR Collection

Headspace ND18 vials with screw neck manufactured from 1st hydrolytic class borosilicate glass with a round bottom. They can be purchased with a variety of magnetic aluminium screw caps and septa materials.

Supplier: Avantor

Avantor® ACE® CN kolommen bieden een uitstekende reproduceerbaarheid en levensduur van de kolom.

Supplier: HAMMERBACHER

Carcass construction, i.e. each cabinet can stand alone.

Supplier: Restek

Viva C18 are monomeric octadecylsilane columns, highly base deactivated wide pore packing that exhibits peak shape for a wide range of compounds from acidic through slightly basic. General purpose column for analyzing large molecules and biomolecules.