11723 Results for: "Enzo Life Sciences"
Daptomycin ≥93% (by HPLC)
Supplier: Enzo Life Sciences
Lipopeptide antibiotic
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Spectinomycin dihydrochloride pentahydrate ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Aminocyclitol antibiotic active against Gram-negative and Gram-positive bacteria (Gonnococcus only). In clinical use for gonorrhea. Inhibits protein synthesis (elongation) by interfering with peptidyl tRNA translocation. Binds to the 30S subunit of bacterial ribosomes. Mutation in rpsE (the gene for ribosomal protein S5) prevents binding of spectinomycin.
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Hematopoietic library, Screen-Well®
Supplier: Enzo Life Sciences
The Screen-Well® hematopoietic toxicity library is a focused collection of 115 compounds with defined and diverse hematopoietic toxicity, including myelosuppression, neutropenia, leukopenia, anaemia, and many more. A variety of structurally and mechanistically different compound classes are included, as well as nontoxic controls. The compounds are dissolved in DMSO at 10 mM and aliquoted into deep-well plates. The library is an essential tool for predictive toxicology screening and assay development.
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Why Choose Corning Fetal Bovine Serum?
Our vertically integrated FBS serum supply chain, from collection to scientist, allows us to provide a consistent supply of FBS.
Clindamycin hydrochloride ≥95% (by HPLC)
Supplier: Enzo Life Sciences
Active against Gram-positive bacteria. Clindamycin binds to the 50S subunit of bacterial ribosomes and suppresses protein synthesis.
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(S)-(+)-Ketoprofen ≥98.5% (by HPLC)
Supplier: Enzo Life Sciences
Active enantiomer of ketoprofen. Inhibits cyclooxygenase.
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Fluorometric drug discovery assay kit, SIRT5, Fluor-de-Lys®
Supplier: Enzo Life Sciences
The SIRT5 Fluorometric Drug Discovery Kit is a sensitive fluorometric assay is designed to measure the lysyl desuccinylase activity of the recombinant human SIRT5.
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Human recombinant Lyn B (GST-tag),GST Tag
Supplier: Enzo Life Sciences
Produced in insect cells. Full length active enzyme.
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Human recombinant PKCι (GST-tag),GST Tag
Supplier: Enzo Life Sciences
Produced in insect cells. Active, full length protein kinase C iota (PKCι), also known as PKCι.
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Dihydroergocristine methanesulphonate ≥98%, white solid
Supplier: Enzo Life Sciences
Serotonin receptor ligand.
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Anti-IgG Mouse Polyclonal Antibody (HRP (Horseradish Peroxidase))
Supplier: Enzo Life Sciences
Immunoglobulin G (IgG) is an immunoglobulin monomer consisting of two (gamma) heavy chains and two light chains. Each IgG molecule contains two antigen binding domains and a single effector (Fc) domain. Assay designs offers isotyping kits and antibodies in a variety of formats for the detection of human, mouse, rabbit, rat, sheep, and goat IgG.
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PPP ≥98% (by HPLC)
Supplier: Enzo Life Sciences
A potent and selective inhibitor of insulin-like growth factor 1 receptor (IGF-1R, IC50=6 nM). It efficiently blocks IGF-1R activity, reduces pAKT and pERK1/2, induces apoptosis in IGF-1R-positive tumor cells and causes complete tumor regression in xenografted and allografted mice. Picropodophyllin downregulates IGF-1R by interfering with the action of β-arrestin 1/MDM2. It causes tumor regression and attenuates invasiveness of uveal melanoma cells. It displays beneficial effects on tumor growth, angiogenesis, bone disease and survival in a mouse multiple myeloma model. It attenuates intimal hyperplasia after vascular injury. Inhibition of IGF-1R is non-competitive with ATP.
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ZM 447439 ≥98% (by TLC)
Supplier: Enzo Life Sciences
ZM-447439 is a potent and selective inhibitor of Aurora B kinase (IC50=50nM), Aurora A and C are inhibited at higher concentrations (IC50=1000nM and 250nM respectively). Other kinases such as Cdk1 and PLK1 are not inhibited (up to 10mM). Cells treated with ZM-447439 progress through interphase, enter mitosis and assemble bipolar spindles but chromosome alignment, segregation and cytokinesis all fail.
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Granzyme B assay kit for drug discovery
Supplier: Enzo Life Sciences
The Granzyme B Assay Kit for Drug Discovery is a complete assay system designed to measure the protease activity of granzyme B. It contains a colorimetric substrate (IEPD-pNA) to measure this activity; cleavage of the p-nitroanilide (pNA) group from the colorimetric substrate increases absorption at 405 nm.
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Sulindac Sulphide ≥99% (by TLC)
Supplier: Enzo Life Sciences
Active metabolite of sulindac. Inhibits cyclooxygenase. More selective for PGHS-1 (ID50=0.5 µM) over PGHS-2 (ID50=14 µM). Induces apoptosis by a cyclooxygenase-independent mechanism. Inhibits colorectal cancer growth and γ-secretase. NF-κB inhibitor. Inhibits Ras signaling.
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7-Aminoactinomycin D (7-AAD)
Supplier: Enzo Life Sciences
7-Aminoactinomycin D is a fluorescent, intercalating DNA-binding agent useful for identifying apoptotic cells by flow cytometry. It is capable of identifying populations representing live, apoptotic, and late apoptotic/dead cells.
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AS601245 sum of isomers ≥95% (by HPLC)
Supplier: Enzo Life Sciences
Jnk inhibitor
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12(S)-HETE ELISA kit
Supplier: Enzo Life Sciences
Sensitive ELISA kit enabling detection of 12(S)-HETE in culture supernatants and plasma from any species.
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Big endothelin-1 (human), ELISA kit
Supplier: Enzo Life Sciences
The Big Endothelin-1 (Human), EIA kit is a colorimetric immunometric enzyme immunoassay kit with results overnight +1 hour.
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Dimethyl-bisphenol A ≥98% (by TLC)
Supplier: Enzo Life Sciences
A HIF-1α degradation promotor.
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Anti-Apaf-1 Rabbit Polyclonal Antibody
Supplier: Enzo Life Sciences
Apaf-1 (Apoptosis protease-activating factor 1), a mammalian protein homologous to C. elegans CED-4, is an essential adaptor molecule and a key linker of the mitochondrial apoptotic pathway.
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MPLA (from E.coli) ≥99.9% serotype R515 (Re), TLRgrade™ ready-to-use
Supplier: Enzo Life Sciences
TLR4 activator.
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Moniliformin sodium salt ≥98% (by TLC)
Supplier: Enzo Life Sciences
Mycotoxin.
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Lipid A 1 mg/ml in water (from E.coli), Serotype R515 (Re) ≥99.9% serotype J5 (Rc), TLRgrade™ ready-to-use non pyrogenic, sterile
Supplier: Enzo Life Sciences
TLR4 activator.
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Anti-IgG Goat Polyclonal Antibody (AP (Alkaline Phosphatase))
Supplier: Enzo Life Sciences
Immunoglobulin G (IgG) is an immunoglobulin monomer consisting of two (gamma) heavy chains and two light chains. Each IgG molecule contains two antigen binding domains and a single effector (Fc) domain. Assay Designs offers isotyping kits and antibodies in a variety of formats for the detection of human, mouse, rabbit, rat, sheep, and goat IgG.
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Anti-PSCA Rabbit Polyclonal Antibody
Supplier: Enzo Life Sciences
PSCA (prostate stem cell antigen) is a cell surface antigen overexpressed in primary prostate cancers and in as many as 100% of metastatic cancers. Antibodies directed against PSCA inhibit tumorigenesis, slow tumor growth, prolong survival, and prevent metastasis in a preclinical xenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.
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Anti-IgG Goat Polyclonal Antibody (HRP (Horseradish Peroxidase))
Supplier: Enzo Life Sciences
Immunoglobulin G (IgG) is an immunoglobulin monomer consisting of two (gamma) heavy chains and two light chains. Each IgG molecule contains two antigen binding domains and a single effector (Fc) domain. Assay Designs offers isotyping kits and antibodies in a variety of formats for the detection of human, mouse, rabbit, rat, sheep, and goat IgG.
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Sorafenib (BAY 43-9006) ≥95% (by HPLC)
Supplier: Enzo Life Sciences
Broad-spectrum kinase inhibitor
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Supplier: GRANT INSTRUMENTS
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