Human recombinant CD40:Fc
Supplier: Enzo Life Sciences
Produced in HEK 293 cells. The cysteine-rich region (aa 21-193) of human CD40 is fused to the Fc portion of human IgG1.
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Human recombinant TNF alpha (soluble) (from E. coli)
Supplier: Enzo Life Sciences
Produced in E. coli. The extracellular domain of human TNF-α (tumor necrosis factor-α) (aa 85-223) is fused at the N-terminus to a linker peptide (8 aa) and a FLAG®-tag.
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Human Recombinant CD137:Fc
Supplier: Enzo Life Sciences
Produced in HEK 293 cells. The cysteine-rich region of human CD137 (4-1BB) (aa 1-186) is fused to the Fc portion of human IgG1.
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Why Choose Corning Fetal Bovine Serum?
Our vertically integrated FBS serum supply chain, from collection to scientist, allows us to provide a consistent supply of FBS.
Human Recombinant CD134:Fc
Supplier: Enzo Life Sciences
Produced in HEK 293 cells. The cysteine-rich region of human CD134 (OX40) (aa 29-214) is fused to the Fc portion of human IgG1.
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Human recombinant TNF-R1:Fc
Supplier: Enzo Life Sciences
Produced in HEK 293 cells. The extracellular domain of human TNF-R1 (aa 1-211) is fused to the Fc portion of human IgG1.
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Anti-RANKL Mouse Monoclonal Antibody
Supplier: Enzo Life Sciences
Host: Mouse, Isotype: IgG1 kappa
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Anti-N-Acetylglucosamine Mouse Monoclonal Antibody
Supplier: Enzo Life Sciences
Host: Mouse, Isotype: IgG3
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Anti-Poly(Adp-Ribose) Mouse Monoclonal Antibody
Supplier: Enzo Life Sciences
Host: Mouse, Isotype: IgG3
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Anti-FASLG Mouse Monoclonal Antibody
Supplier: Enzo Life Sciences
Host: Mouse, Isotype: IgG1
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Anti-HTRA2 Mouse Monoclonal Antibody
Supplier: Enzo Life Sciences
Host: Mouse, Isotype: IgG1
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Anti-BIML Rat Monoclonal Antibody
Supplier: Enzo Life Sciences
Host: Rat, Isotype: IgG2b
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Anti-TLR3 Mouse Monoclonal Antibody
Supplier: Enzo Life Sciences
Host: Mouse, Isotype: IgG1
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Anti-CASP11 Rat Monoclonal Antibody
Supplier: Enzo Life Sciences
Caspase-11 not only activates caspase-1, that is required for the maturation of proinflammatory cytokines such as interleukin-1 (IL-1) and interleukin-18 (IL-18), but also activates caspase-3, leading to cellular apoptosis under pathological conditions. In most cells, caspase-11 is only expressed upon induction with pro-inflammatory stimuli. Caspase-11 is an essential mediator of endotoxic shock and caspase-11-deficient mice are resistant to endotoxic shock. LPS-induced caspase-11 regulates lymphocyte apoptosis by activating both caspase-3 and caspase-7. Human caspase-4, thought to be the homolog of mouse caspase-11, may be an effective therapeutic target for treatment of septic shock.
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Anti-CCL22 Rat Monoclonal Antibody
Supplier: Enzo Life Sciences
Host: Rat, Isotype: IgG
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Anti-HIF1A Mouse Monoclonal Antibody
Supplier: Enzo Life Sciences
Oxygen availability plays a major role in the regulation of expression of many different genes including erythropoietin, nitric oxide synthase (NOS), heme oxygenase 1 (HO-1), glucose transporters and vascular growth factors necessary for the maintenance of homeostasis in hypoxic conditions. Hypoxia-inducible factor 1α (HIF-1α) has been identified as a bHLH-PAS family member which is instrumental in the oxygen-dependent regulation of these genes. HIF-1α rapidly accumulates in the nucleus upon exposure to hypoxic conditions where it heterodimerizes with the aryl hydrocarbon nuclear receptor translocator, ARNT, also referred to as HIF-1β.
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L(-)-Glutathione (reduced form)
Supplier: Enzo Life Sciences
L(-)-Glutathione (reduced form)
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ETA receptor antagonist [BQ-610]
Supplier: Enzo Life Sciences
30-fold more potent ETA antagonist than BQ-123 in pig aortic smooth muscle membrane assay, same activity as BQ-123 when tested on pig cerebellum membrane.
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Pam3Cys-Ser-(Lys)4 . trihydrochloride
Supplier: Enzo Life Sciences
Selective agonist of TLR1/TLR2 complex
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Ras inhibitory peptide
Supplier: Enzo Life Sciences
The peptide sequence corresponds to amino acid residues 1149-1158 of the guanine nucleotide-releasing factor hSos1, which is essential for the control of Ras activity. Blocks the binding of hSos1 to human Grb2, a protein that binds to activated receptor tyrosine kinases.
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D-myo-Inositol-1,4,5-trisphosphate triammonium salt ≥98% (by HPLC)
Supplier: Enzo Life Sciences
D-myo-Inositol-1,4,5-trisphosphate triammonium salt ≥98% (by HPLC)
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Anti-FAS Mouse Monoclonal Antibody
Supplier: Enzo Life Sciences
Host: Mouse, Isotype: IgG3
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KillerTRAIL™ storage and dilution buffer
Supplier: Enzo Life Sciences
Storage and dilution buffer for use with the following products:
KillerTRAIL™, Soluble (human) (recombinant) (Prod. No. ALX-201-073)
SuperKillerTRAIL™, Soluble (human) (recombinant) (Prod. No. ALX-201-115)
SuperKillerTRAIL™, Soluble (mouse) (recombinant) (Prod. No. ALX-201-130)
Useful for prediluting the above mentioned products before preparing aliquots or performing experiments. Predilution with KillerTRAIL™ Storage and Dilution Buffer allows for easier handling of small working concentrations (sometimes only 0.1µl of the KillerTRAIL™ or SuperKillerTRAIL™ stock solution is necessary because of their high activity). Predilution with KillerTRAIL™ Storage and Dilution Buffer instead of medium or PBS prevents loss of biological activity. Can also be used as negative control.