11722 Results for: "ENZO LIFE SCIENCES"

Supplier: Enzo Life Sciences

Arachidonic acid metabolite.

Supplier: Enzo Life Sciences

Multidrug resistance transporter activator.

Supplier: Enzo Life Sciences

Cell permeable antagonist of L-type Ca2+ channels in C. elegans and vertebrates.

Supplier: Enzo Life Sciences

This kit is useful for assaying lysates, immunoprecipitates or inhibitor screening using the nuclear extract provided. Includes HeLa nuclear extract, a rich source of HDACs 1 & 2 for use as a positive control or as a source of HDAC activity for screening. Compatible with class I & IIb HDAC and sirtuins (with addition of NAD+).

Supplier: Enzo Life Sciences

A QuantiZyme™ Assay System. The MMP-9 Colorimetric Drug Discovery Kit is a complete assay system designed to screen inhibitors of matrix metalloproteinase-9 (MMP-9, gelatinase B) using a thiopeptide as a chromogenic substrate.

Supplier: Enzo Life Sciences

A QuantiZyme™ Assay SystemThe MMP-7 Colorimetric Drug Discovery Kit is a complete assay system designed to screen inhibitors of matrix metalloproteinase-7 (MMP-7, matrilysin) using a thiopeptide as a chromogenic substrate.

Supplier: Enzo Life Sciences

The HDAC2 Fluorescent Activity Assay/Drug Discovery Kit is a complete assay system designed to measure the lysyl deacetylase activity of the recombinant human HDAC2 included in the kit. The kit is ideal for chemical library screening for candidate inhibitors or kinetic assay of the enzyme under varying conditions.

Supplier: Enzo Life Sciences

Potent inhibitor of VEGFRs

Supplier: Enzo Life Sciences

Selective inhibitor of JAK1 and JAK2 kinases including the JAK2 V617F mutant

Supplier: Enzo Life Sciences

Inhibitor of PDK1, TBK1, IKK-ε, IRF3

Supplier: Enzo Life Sciences

The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. Toll-like receptor 4 (TLR4), the principal signaling receptor for lipopolysaccharide (LPS) in mammals, requires the binding of MD-2 to its extracellular domain for maximal responsiveness. MD-2 enables TLR4 to respond to a wide variety of LPS partial structures, Gram-negative bacteria, and Gram-positive lipoteichoic acid, but not to Gram-positive bacteria, peptidoglycan, and lipopeptide.

Supplier: Enzo Life Sciences

Dimethylargininase (DDAH) is a Cys-hydrolase, which, through catabolism of mono- and dimethylated derivatives of L-arginine, regulates the activity of nitric oxide synthase. DDAH-1 is mainly present in tissues expressing the constitutive forms of nitric oxide synthase such as brain and kidney.

Supplier: Enzo Life Sciences

mTOR (FKBP12-rapamycin associated protein (FRAP)) is one of a family of proteins involved in cell cycle progression, DNA recombination, and DNA damage detection. It has been shown to associate with the immunophilin FKBP12 in a rapamycin-dependent fashion. FKBP12-rapamycin-binding (FRB) domain is a conserved 11kDa region necessary for FKBP12-rapamycin binding. FRB is one of several functional domains of mTOR: HEAT (Huntington elongation factor 1A-protein phosphatase 2A-A subunit-TOR); FAT (FRAP, ATM, TTRAP2); PIKK (PI3-kinase-related kinase); RD (regulatory domain); and FATC (FAT, C terminal).

Supplier: Enzo Life Sciences

Most sensitive ELISA kit, enabling reduced input sample, for the quantification of human haptoglobin, a potent immunosuppressor and stimulator of angiogenesis.

Supplier: Enzo Life Sciences

Rapid ELISA kit to quantify hepsin, a serine protease and unique cancer biomarker.

Supplier: Enzo Life Sciences

PARP inhibitor

Supplier: Enzo Life Sciences

Orally bioavailable 284 D-1,2,4-oxadiazole.

Supplier: Enzo Life Sciences

Necroptosis inhibitor

Supplier: Enzo Life Sciences

Necroptosis inhibitor

Supplier: Enzo Life Sciences

DNA synthesis inhibitor

Supplier: Enzo Life Sciences

Selective ligand for toll-like receptor 7 (TLR7) via IFN.

Supplier: Enzo Life Sciences

The liquid cell lysis buffer composes of 20 mM TRIS, pH 7,4, containing 500 mM sodium chloride, 10 mM EDTA, 1% Triton X-100, 20 mM sodium fluoride, 20 mM beta-glycerophosphate.

Supplier: Enzo Life Sciences

Cell lysis buffer 4, Enzo Life Sciences

Supplier: Enzo Life Sciences

Beneficial effects in cardiovascular diseases and inflammation.

Supplier: Enzo Life Sciences

Cytochrome P450 substrate

Supplier: Enzo Life Sciences

The Screen-Well® histaminergic and melatonin ligands plate contains 41 ligands including endogenous neurotransmitters, agonists, antagonists, and marketed drugs. The library is ideal for screening or identifying recombinant orphan G protein coupled receptors, target validation, secondary screening, assay development, and other pharmacological applications. The Histaminergic and Melatonin Ligands plate is 1 plate of the larger neurotransmitter library which contains over 680 ligands.

Supplier: Enzo Life Sciences

SCREEN-WELL® orphan ligand library contains 84 compounds with defined, putative, potential or speculative biological activity but whose protein binding partners have not been identified.

Supplier: Enzo Life Sciences

TLR9 ligand.

Supplier: Enzo Life Sciences

Inhibits platelet aggregation. Inhibitor of Epstein-Barr virus early antigen (EBV-EA) induction. Exhibits potent inhibitory effect on skin tumor promotion. Potent inhibitor of MMP-2. Displays DNA strand-scission (cleaving) activity. Shows antifungal activity.

Supplier: Enzo Life Sciences

TLR9 ligand.