7875 Results for: "Bioworld Technology"

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GALNT3 polyclonal antibody detects endogenous levels of GALNT3 protein 1 * 100 µG

Supplier: Bioworld Technology

PARP pAb detects endogenous levels of full length PARP1 (116 kDa), as well as the large fragment (89 kDa) of PARP1 resulting from ca spase cleavage 1 * 100 µG

Supplier: Bioworld Technology

HGD polyclonal antibody detects endogenous levels of HGD protein 1 * 100 µG

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Acts as a transcriptional regulator. Inhibits myogenesis by sequestrating E proteins, inhibiting trans-activation by MEF2, and inhib iting DNA-binding by MYOD1 through physical interaction. 1 * 100 µG

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A critical step in signal transduction responses to stimulation of cell surface receptors by their ligands involves the accumulation of Ras proteins in their active GTP-bound state. To reach their active GTP-bound state, Ras proteins must first rele 1 * 100 µG

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BECN1 (beclin 1) is a coiled-coil protein that has been implicated as an inhibitor of tumorigenesis. BECN1, which associates with Bc l-2, plays a significant role in autophagy. 1 * 100 µG

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Occludin is an integral membrane protein closely associated with the tight junctions of epithelial and endothelial cells. Occludin i s a tetraspan integral membrane protein in epithelial and endothelial tight junction (TJ) structures. 1 * 100 µG

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This gene encodes a member of the canonical subfamily of transient receptor potential cation channels. The encoded protein forms a n on-selective calcium-permeable cation channel that is activated by Gq-coupled receptors and tyrosine kinases. 1 * 100 µG

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IFT88 (Intraflagellar transport protein 88), also known as TG737 or TTC10 (TPR repeat protein 10), is an 833 amino acid protein that contains 12 TPR repeats and belongs to the TPR family. 1 * 100 µG

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DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. The fa mily is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosin 1 * 100 µG

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The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with huma n cofactor C, a protein involved in the ultimate step of beta-tubulin folding. 1 * 100 µG

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This gene is a member of a photoreceptor-specific gene family and encodes an integral membrane protein found in the photoreceptor di sk rim of the eye. This protein can form homodimers or can heterodimerize with another photoreceptor, retinal degener 1 * 100 µG

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The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date. 1 * 100 µG

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The human IL-3, IL-5 and GM-CSF receptors are each composed of both unique a subunits and a common β subunit. The a subunits are low affinity ligand binding proteins while the β subunits do not themselves bind ligand, but are required for high affin 1 * 100 µG

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The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date. While the biological activit ies of these receptors have yet to be determined, there is increasing evidence that they are involved in central nerv 1 * 100 µG

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This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act a s ligand-dependent transcriptional regulators. 1 * 100 µG

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This gene is a member of the calcium/calmodulin-dependent protein kinase 1 family, a subfamily of the serine/threonine kinases. The encoded protein is a component of the calcium-regulated calmodulin-dependent protein kinase cascade. 1 * 100 µG

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Desmoglein proteins are cadherin-type cell adhesion molecules. Desmoglein 4 (dsg4) shares 41% identity with human desmoglein 1, 37% with human desmoglein 2 and 50% with human desmoglein 3. 1 * 100 µG

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Phosphatidylinositol-glycans (PIGs) are multi-pass transmembrane proteins that localize to the endoplasmic reticulum. PIGs exhibit v arious functions, but all are crucial for the biosynthesis of the glycosylphosphatidylinositol (GPI)-anchor. 1 * 100 µG

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The transcriptional enhancer factor (TEF)/TEAD family includes TEF-1, TEF-3, TEF-4 and TEF-5. These proteins share a highly conserve d 68-amino acid TEA/ATTS DNA-binding domain, which binds to SV40 GT-IIC (GGAATG), SphI (AGTATG), SphII (AGCATG), and 1 * 100 µG

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RP105 is a mouse B-cell surface molecule that transmits a growth-promoting signal and is implicated in the life/death decision of B cells. RP105 has tandem repeats of a leucine-rich motif in its extracellular domain that are presumed to be involved i 1 * 100 µG

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Ox40 (also designated CD134 and Ox40R), is a member of the tumor necrosis factor receptor (TNFR) family. Ox40 is involved in coordin ating CD4 T cell selection, migration and cytokine differentiation in T helper (Th)1 and Th2 cells. 1 * 100 µG

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Rab11-FIP1 (Rab 11 family-interacting protein 1), also known as Rab-coupling protein (RCP), is a 1283 amino acid Rab 11 effector pro tein. Rab11-FIP1, by interacting with Rab GTPases. 1 * 100 µG

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The Per-Arnt-Sim (PAS) domain is a 270 amino acid motif that mediates associations among various PAS family transcription factors. T he PAS family contains neuronal specific transcription factors known as NPAS1, NPAS2, NPAS3 and NPAS4. 1 * 100 µG

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Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcri ptional activation or repression. 1 * 100 µG

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Glycogen [starch] synthase belongs to the mammalian/fungal glycogen synthase family of proteins. Two forms of this protein exist, a liver form and a muscle form, both of which have the same function in the glycogen biosynthesis pathway. 1 * 100 µG

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DNA containing double-strand breaks (DSB) created by the CRISPR/Cas9 system can be repaired by either the non-homologous end-joining (NHEJ) or the homology-directed repair (HDR) pathway. 1 * 100 µG

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RBM29 (RNA binding motif protein 29), also known as ELMOD3 (ELMO domain-containing protein 3) or RBED1 (RNA-binding motif and ELMO d omain-containing protein 1), is a 381 amino acid protein that contains one ELMO domain and exists as six alternativel 1 * 100 µG

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CD32 (also designated Fc gamma RII) is a low affinity receptor for the Fc fragment of aggregated IgG. CD32 is responsible for the cl earance of immunocomplexes by macrophages and also plays an important role in the regulation of antibody production b 1 * 100 µG

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HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integr ated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on 1 * 100 µG