62577 Results for: "Amberlyst®+A-21&pageNo=50&view=list"

Supplier: Spectrum Chemical

L-Arginine hydrochloride USP

Supplier: STEMCELL Technologies

Interleukin 3 (IL-3) is a species-specific pleiotropic cytokine that promotes the survival and proliferation of pluripotent hematopoietic stem cells and lineage-committed progenitor cells and their differentiation into mature cells of most lineages, including basophils, neutrophils, eosinophils, macrophages, dendritic cells, erythrocytes, and megakaryocytes (Yang et al.; Dorssers et al.; Broughton et al.). IL-3 is produced by activated T cells and has a physiological role in inflammation and allergies by promoting the secretion of inflammatory mediators such as histamine, IL-4, and IL-6 by basophils and eosinophils (Broughton et al.). The IL-3 receptor consists of a unique alpha subunit (CD123) and a beta common subunit (βc or CD131) that is shared with the receptors for IL-5 and GM-CSF, and is the principal signal transduction subunit for these cytokines. IL-3 binding to the heterodimeric receptor activates JAK/STAT, MAPK, and PI3K signaling pathways (Woodcock et al.).

Supplier: Roth Carl

L-Arginine hydrochloride

Supplier: STEMCELL Technologies

Oncostatin M (OSM) is a member of interleukin 6 (IL-6) family of cytokines and bears close resemblance to leukemia-inhibitory factor (LIF) and granulocyte colony-stimulating factor (G-CSF) in amino acid sequence and its modulation of differentiation in a variety of cell types (Rose and Bruce). OSM signals through type I receptor (consisting of gp130 and LIF receptor (LIFR)) and type II receptor (consisting of gp130 and OSM receptor (OSMR)), which eventually activate the JAK/STAT pathway (Auguste et al.; Gómez-Lechón). OSM is primarily produced by activated T cells and monocytes, and also by activated macrophages, neutrophils, mast cells, and dendritic cells. OSM is also produced within the bone microenvironment by cells of both hematopoietic and mesenchymal origin including osteocytes and osteoblasts. OSM is involved in differentiation, cell proliferation, hematopoiesis, and inflammation, and also has been shown to have implications in liver development, bone formation and resorption (Sims and Quinn; Tanaka and Miyajima).

Supplier: Systec GmbH

für Stützdruck in der Kühlphase für Systec V-55 bis Systec V-150, Systec D-23 bis Systec D-200 und Systec HX-65 bis Systec HX-200 1 * 1 ST

Supplier: STEMCELL Technologies

Fibroblast growth factor 7 (FGF-7) is a member of the FGF family, and acts exclusively through a subset of FGF receptor isoforms expressed predominantly by epithelial cells (Finch and Rubin). FGF-7 seems to act specifically on epithelial cells and stimulates proliferation, migration, and differentiation of these cells, and also participates in epithelial protection and repair both in vitro and in vivo (Finch and Rubin; Werner). In contrast, FGF-7 is produced solely by cells of mesenchymal origin, and functions as a paracrine mediator of mesenchymal-epithelial communication (Rubin et al.). FGF-7 has also been shown to supplement several wound-healing properties of bioengineered skin (Erdag et al.) and to induce autophagy in human keratinocytes (Belleudi et al.). Additionally, FGF-7 has a role in pluripotent stem cell differentiation to endodermal pancreatic-like insulin-producing cells and thymic epithelial cells (Inami et al.; Niu et al.).

Supplier: STEMCELL Technologies

Interleukin 10 (IL-10) is the founding member of the IL-10 family of class II cytokines. All of the IL-10 cytokine family members have a four-helix bundle consisting of α-helical folds. Upon binding to its receptor, IL-10 activates signaling through JAK1 and STAT3. It is produced by dendritic cells, macrophages, and CD4+ T cells, as well as mast cells, NK cells, neutrophils, and B cells, under specific stimulating conditions (Saraiva and O'Garra). IL-10 can inhibit the expression of pro-inflammatory cytokines and promote healing processes, and is important for the function of regulatory T cells. IL-10 also enhances B cell proliferation, immunoglobulin secretion, and class II MHC expression, while IL-10 produced by macrophages inhibits activation of neighboring macrophages, thus allowing a level of self-regulation (Ouyang et al.).

Supplier: Halyard

Extended length PUREZERO® life science nitrile gloves deliver on all fronts. They are tested against 57 chemicals, with 3 levels of colour-coded protection offering increasing thickness designed for life science applications. The SAFESKIN® manufacturing facility uses 92% renewable energy, dispensers are made with up to 85% recycled materials, and cases are made with up to 99% recycled pulp.

Supplier: Thermo Fisher Scientific

For customers in cell and gene therapy and vaccine production, the CryoMed with OPC UA provides precise, repeatable freezing results that protect samples from intracellular freezing. The CryoMed features OPC UA serial communication (ethernet) capabilities, comes standard factory certifications, provides enhanced data traceability via a touch screen user interface and offers customizable freezing profiles while supporting 21 CFR part 11 and GMP needs.

Supplier: STEMCELL Technologies

Interferon gamma-inducible protein (IP) 10 or CXCL10 is a member of the CXC chemokine family. It binds CXCR3 activating ERK1/2, p38/MAPK, JNK, and PI3-kinase/AKT signaling pathways, inducing intracellular calcium influx, DNA synthesis, cell proliferation, and chemotaxis. IP-10 regulates innate and adaptive immune responses by affecting the function of activated T cells, natural killer cells, inflammatory dendritic cells, macrophages, and B cells. IP-10 is produced by leukocytes, activated neutrophils, eosinophils, monocytes, epithelial cells, endothelial cells, fibroblasts, and keratinocytes in response to IFN-gamma. IP-10 has been implicated in a wide range of diseases, including infectious diseases and chronic inflammatory and autoimmune diseases, as well as in tumor formation (Liu et al.).

Supplier: STEMCELL Technologies

Epidermal growth factor receptor (EGFR) is a type I transmembrane protein and receptor tyrosine kinase. EGFR has been shown to bind to some members of the EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, epiregulin, heparin-binding EGF, and neuregulin-2α. EGFR ligand binding induces homodimerization, as well as heterodimerization of EGFR with ErbB2 or with ligand-activated ErbB3 or ErbB4 (Schlessinger). Dimerization results in kinase activation, phosphorylation, and cell signaling, mediated primarily through MEK/ERF and AKT pathways (Navlonic et al.). EGFR signaling has been shown to regulate cell proliferation, differentiation, motility, and apoptosis. Elevated levels of EGFR have been correlated with carcinogenesis (Maihle et al.). Protein contains a His-residue tag at the carboxyl end of the polypeptide chain.

Supplier: JUCHHEIM Laborgerate GmbH

verstellb.Blattruhrer fur NS29, 250-500 ml 1 * 1 ST

Supplier: MEGAZYME

PECTYTE LYASE EC 4.2.2.2 1 * 1 ST

Supplier: ZWIEBEL

BRASS MASS 50G WITH CERTIFICATE 1 * 1 items

Supplier: QIAGEN

RNase-Free DNase Set 1 * 1 SET

Supplier: Socorex Isba

SOC VERNIER 50ÁL 1 * 1 items

Supplier: witeg Labortechnik

FLASK 50ML CLAISENUPPSATS 1 * 1 items

Supplier: MORGAN ADVANCED MATERIALS HALD

ALSINTTUBE 60X50X1000MM 1 * 1 items

Supplier: HIRSCHMANN

Spare piston for akku-drive 50ml 1 * 1 items

Supplier: Amarell

Thermometer similar to IP 44 C, solid stem, white backed, 15+121:0,5°C, red special liquid, durable pigment, suitable for government calibration 1 * 1 items

Supplier: GERHARDT

DIAPHRAGM PUMP FOR NAOH 1 * 1 items

Supplier: MEGAZYME

D-/L-LACTIC ACID ASSAY KIT 1 * 100 Assays

Supplier: Stirling Ultracold

The Stirling VAULT100 is the first ULT freezer with a −100 to −20 °C temperature range and the best steady-state setpoint adherence in the market.

Supplier: Merck

Milli-Q® EQ 7008/7016 ultrapure and reverse osmosis (RO, Type 3) water systems are designed to produce consistent ultrapure water quality [resistivity 18,2 MΩ.cm at 25 °C; total organic carbon (TOC) ≤5 ppb] direct from a tap water source. Final ultrapure water quality can be adapted to each user’s specific application requirements. Plus, a range of intelligent design features make it effortless to dispense water as needed and where needed in the lab.

Supplier: LAMAPLAST

BIN 50L GREEN 1 * 1 items

Supplier: PHENOMENEX

STRATA SI-1 SILICA (55UM, 70A)500MG/12ML 1 * 20 items

Supplier: Palintest

Starter Pack Calcium Hardness 1 * 1 Each

Supplier: QVF LABORTECHNIK

SOLVENT FLOW APPARATUS W/ 500ML VESSEL 1 * 1 items

Supplier: Amarell

Precision therm., straight stem, -5+100:0,2C, capillary tube specially coated inside, with non-wetting blue special liquid, upper part 350x11mm, lower part 100x7-8mm, null

Supplier: LAMAPLAST

BIN 50L YELLOW 1 * 1 items