62585 Results for: "Amberlyst®+A-21&pageNo=50&view=list"

Supplier: VELP SCIENTIFIC

The OHS Series overhead stirrers are the ideal solution for the most demanding applications: The powerful brushless motor and microprocessor ensure excellent performance and make the VELP OHS Series overhead stirrers unlike any conventional stirrer.

Supplier: KGW

COLD TRAP TYP KF 54V-K16-Z-360 1 * 1 items

Supplier: Epredia

Microslide cut frosted 20mm glass cello ISO 8037/1 1,0mm 1 * 2.000 items

Supplier: Kavalier

FLASK ROUND 1L BORO 3.3 WIDE NECK 1 * 10 items

Supplier: KNITTEL

THERM. PRINT. SLIDE ADV. ADH. 90° GRD ED 1 * 1.500 items

Supplier: Epredia

Microslide 90° frosted 20mm glass cello ISO 8037/1 1,0mm 1 * 2.000 items

Supplier: Epredia

Microslide Superfrost 90° CC yellow glass cello ISO 8037/1 1,0mm 1 * 2.000 items

Supplier: FISHER CONTAINER

[EN]TUBING 70 MM TYVEK 1059B / PET 48 G 1 * 20 Rolle

Supplier: SAMCO

PIPETTE T/FER EXT/F/TIP STER PE 35.4ML 1 * 4.000 items

Supplier: Epredia

Microslide Superfrost 90° CC yellow glass cello ISO 8037/1 1,0mm 1 * 1.000 items

Supplier: Greiner Bio-One

TUBES PP CONICAL 50ML S/CAP SKIRTBASE P/25KIEMVR. 1 * 450 items

Supplier: Epredia

Microslide Superfrost 90° CC white glass with box cello ISO 8037/1 1,0mm 1 * 2.000 items

Supplier: Epredia

Microslide Superfrost 45° green glass with box cello ISO 8037/1 1,0mm 1 * 2.000 items

Supplier: Epredia

Microslide 45° frosted 20mm glass cello ISO 8037/1 1,0mm 1 * 2.000 items

Supplier: Thermo Scientific

Uv-c irradiator spot k 115 v 60 hz 1 * 1 items

Supplier: Greiner Bio-One

FOAM PLUG 50MM CEAPRENE 1 * 315 items

Supplier: MARKET SOURCE PART PROCESS

1 OFF SF10 REAGENT PUMP 100 240 VAC 1 * 1 items

Supplier: Epredia

Microslide Superfrost 45° white glass with box cello ISO 8037/1 1,0mm 1 * 2.000 items

Supplier: Epredia

Microslide Superfrost 90° CC green glass with box cello ISO 8037/1 1,0mm 1 * 2.000 items

Supplier: Amarell

General purpose thermometer, enclosed scale, cap. lens front, red special liquid, -10+60:1C, total immersion, 200x7-8mm long, with ring at top 1 * 1 items

Supplier: SAMCO

PIPETTE T/FER EXT/F/TIP STER PE 1.7ML 1 * 3.200 items

Supplier: ProSci Inc.

The Fas is also known as FAS receptor (FasR), apoptosis antigen 1 (APO-1 or APT), cluster of differentiation 95 (CD95) or tumor necrosis factor receptor superfamily member 6 (TNFRSF6). is a death receptor on the surface of cells that leads to programmed cell death (apoptosis). It is one of two apoptosis pathways, the other being the mitochondrial pathway. FasR is located on chromosome 10 in humans and 19 in mice. Similar sequences related by evolution (orthologs) are found in most mammals. Fas forms the death-inducing signaling complex (DISC) upon ligand binding. Membrane-anchored Fas ligand trimer on the surface of an adjacent cell causes trimerization of Fas receptor. This event is also mimicked by binding of an agonistic Fas antibody, though some evidence suggests that the apoptotic signal induced by the antibody is unreliable in the study of Fas signaling. To this end, several clever ways of trimerizing the antibody for in vitro research have been employed.Upon ensuing death domain (DD) aggregation, the receptor complex is internalized via the cellular endosomal machinery. This allows the adaptor molecule FADD to bind the death domain of Fas through its own death domain. Recently, Fas has also been shown to promote tumor growth, since during tumor progression, it is frequently downregulated or cells are rendered apoptosis resistant. Cancer cells in general, regardless of their Fas apoptosis sensitivity, depend on constitutive activity of Fas. This is stimulated by cancer-produced Fas ligand for optimal growth.

Supplier: STEMCELL Technologies

The B18R protein, which is encoded by the B18R open reading frame in the Western Reserve (WR) strain of vaccinia virus, is a type I interferon (IFN)-binding protein that is known to inhibit IFN antiviral response (Colamonici et al.). B18R protein has been shown to exhibit neutralizing activity to type I interferon family members (Meyers et al.) and to protect cells from the antiviral effects of interferon (Vancová et al.). It was recently shown that HIV-1–dependent induction of type I IFN activity and BAFF protein levels was abrogated by the soluble B18R protein, with no effect observed on the cell viability (Gomez et al.). B18R protein has been reported to aid in cellular reprogramming using RNA-mediated gene delivery (Warren et al.; Yoshioka N et al.).

Supplier: ProSci Inc.

tumour Necrosis Factor- alpha (TNF- alpha) is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells following stimulation by bacterial LPS. Cells expressing CD4 secrete TNF- alpha while cells that express CD8 secrete little or no TNF- alpha. Synthesis of TNF- alpha can be induced by many different stimuli including interferons, IL2, and GM-CSF. The clinical use of the potent anti-tumour activity of TNF- alpha has been limited by the proinflammatory side effects such as fever, dose-limiting hypotension, hepatotoxicity, intravascular thrombosis, and hemorrhage. Designing clinically applicable TNF- alpha mutants with low systemic toxicity has been of intense pharmacological interest. Human TNF- alpha that binds to murine TNF-R55 but not murine TNF-R7, exhibits retained anti-tumour activity and reduced systemic toxicity in mice compared with murine TNF- alpha, which binds to both murine TNF receptors. Based on these results, many TNF- alpha mutants that selectively bind to TNF-R55 have been designed. These mutants displayed cytotoxic activities on tumour cell lines in vitro and have exhibited lower systemic toxicity in vivo. Recombinant Human TNF- alpha High Active Mutant differs from the wild-type by amino acid subsitution of amino acids 1-7 with Arg8, Lys9, Arg10 and Phe157. This mutant form has been shown to have increased activity with less inflammatory side effects in vivo.

Supplier: Epredia

Microslide Superfrost 45° yellow glass with box cello ISO 8037/1 1,0mm 1 * 2.000 items

Supplier: JM BROSSERIE

BRUSH CLEAN Ø50MM L=200MM PA WH 0.6MM 1 * 10 items

Supplier: Epredia

Microslide Superfrost 90° CC yellow glass with box cello ISO 8037/1 1,0mm 1 * 2.000 items

Supplier: Epredia

Microslide Superfrost 90° CC blue glass with box cello ISO 8037/1 1,0mm 1 * 2.000 items

Supplier: WATERS

Column Atlantis T3 3um 2.1 x 50mm 1 * 1 Each

Supplier: Epredia

Microslide Superfrost Print 90° yellow glass cello ISO 8037/1 1,0mm 1 * 2.000 items