Supplier: Bioss

Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Involved in early stage of neuronal differentiation via its interaction with NIF3L1.

Supplier: Bioss

The MAGUK (membrane-associated guanylate kinase homologs) family of proteins contain multiple protein-binding domains and are involved in cell junction organization, tumor suppression, and signaling. CASK (also designated LIN-2) belongs to a MAGUK subfamily which is characterized by a novel domain structure that consists of a calcium/calmodulin- dependent protein kinase domain followed by PDZ, SH3 and guanylate kinase-like (GUK) domains. CASK is expressed in rat brain where it binds to cell-surface proteins, such as neurexin and syndecan, and is thought to be involved in signaling at neuronal synapses. CASK translocates to the nucleus and interacts with Tbr-1 to form a complex, which binds to a specific DNA sequence (the T-element), and induces the expression of specific genes, including Reelin. CASK displays a transcription regulation function, which appears crucial for cerebrocortical development.

Supplier: Bioss

The MAGUK (membrane-associated guanylate kinase homologs) family of proteins contain multiple protein-binding domains and are involved in cell junction organization, tumor suppression, and signaling. CASK (also designated LIN-2) belongs to a MAGUK subfamily which is characterized by a novel domain structure that consists of a calcium/calmodulin- dependent protein kinase domain followed by PDZ, SH3 and guanylate kinase-like (GUK) domains. CASK is expressed in rat brain where it binds to cell-surface proteins, such as neurexin and syndecan, and is thought to be involved in signaling at neuronal synapses. CASK translocates to the nucleus and interacts with Tbr-1 to form a complex, which binds to a specific DNA sequence (the T-element), and induces the expression of specific genes, including Reelin. CASK displays a transcription regulation function, which appears crucial for cerebrocortical development.

Supplier: Thermo Fisher Scientific

Zinc sulphide 99.99% (trace metals basis) < 10 µm

Supplier: Thermo Fisher Scientific

Tungsten ≥99% (metals basis), powder -50+100 mesh

Supplier: Thermo Fisher Scientific

Ruthenium 99.9% (trace metals basis), powder -200 mesh

Supplier: Thermo Fisher Scientific

Vanadium ≥99.8% (metals basis), wire, Ø 1.5 mm (0.06 in)

Supplier: Thermo Fisher Scientific

Iron ≥99.99% (metals basis), wire, Ø 1.0 mm (0.04 in)

Supplier: Thermo Fisher Scientific

Indium ≥99.99% (metals basis), wire, Ø 2.0 mm (0.08 in)

Supplier: Thermo Fisher Scientific

Iridium ≥99.95% (metals basis), shot 6-7 mm (0.24-0.28 in)

Supplier: Thermo Fisher Scientific

Iridium ≥99.8% (metals basis), pellets, Ø ∼1.3 cm (0.5 in)

Supplier: Thermo Fisher Scientific

Zinc copper composite ≥99% (metals basis) -100 mesh

Supplier: Thermo Fisher Scientific

Gold ≥99.9% (metals basis), wire, Ø 0.25 mm (0.01 in)

Supplier: Thermo Fisher Scientific

Yttrium ≥99.9% (REO, rare earth oxide basis), pieces

Supplier: Thermo Fisher Scientific

Palladium ≥99.9% (metals basis), foil, Thickness: 0.25 mm

Supplier: Thermo Fisher Scientific

Scandium(III) bromide, ultra dry ≥99.99% (metals basis)

Supplier: Abcam

HRP Rabbit monoclonal [EPR19633] to CRISPR-Cas9.

Supplier: Thermo Fisher Scientific

Cobalt ≥99.998% (metals basis), powder, Puratronic® -22 mesh

Supplier: US Biological

Anti-Calcium-Sensing Receptor CASR Rabbit Polyclonal Antibody

Supplier: MICRONOVA

This tape dispenser is a combination of coated steel and plastic. Designed for use with Micronova tapes of up to 7,62 cm width.

Supplier: Thermo Fisher Scientific

Zinc chloride 99.99% (trace metals basis), extra pure

Supplier: Thermo Fisher Scientific

Cobalt ≥99.95% (metals basis), wire, Ø 1.5 mm (0.06 in)

Supplier: Thermo Fisher Scientific

Chromium ≥99.99% (metals basis), powder -100+325 mesh

Supplier: Thermo Fisher Scientific

Silver nitrate ≥99.995% (metals basis) Ag ≥ 63%, Premion®

Supplier: Thermo Fisher Scientific

Zinc(II) nitrate hexahydrate ≥99.998% (metals basis), Puratronic®

Supplier: Thermo Fisher Scientific

Copper ≥99.9% (metals basis), shot ACS ≤ 6 mm (0.2 in)

Supplier: Thermo Fisher Scientific

Platinum ≥99.9% (metals basis), amorphous powder APS <3 µm

Supplier: Thermo Fisher Scientific

Copper ≥99.99% (metals basis), wire, Ø 0.015 mm (0.0006 in)

Supplier: Thermo Fisher Scientific

Praseodymium(III,IV) oxide 99.9% (trace metals basis)

Supplier: Thermo Fisher Scientific

Manganese ≥99.6% (metals basis), powder APS <10 µm