142775 Results for: "4,4\'-Bipyridyl&pageNo=30"

Supplier: Bioss

Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level.

Supplier: Bioss

MP21 is a member of the EMP24/GP25L/p24 cargo family of proteins that regulates vesicular trafficking in the early secretory pathway. TMP21 is a ubiquitously expressed single-pass type I membrane protein localizing to the Golgi cisternae and the plasma membrane. It contains one GOLD (Golgi dynamics) domain and participates in protein transport and quality control between the endoplasmic reticulum (ER) and the Golgi complex. In addition, TMP21 is a component of the heteromeric secretase complex (or Presenilin complex) and functions to regulate the ?secretase activity. Two isoforms, namely TMP21-I and TMP21-II, exist for this protein.

Supplier: Bioss

Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity. [SUBCELLULAR LOCATION] Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Constituent of focal adhesions.

Supplier: Bioss

RRBP1 (Ribosome-binding protein 1) acts as a ribosome receptor and mediates interaction between the ribosome and the endoplasmic reticulum membrane.

Supplier: Bioss

C19orf38

Supplier: Bioss

Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

Supplier: Bioss

CPXM (carboxypeptidase X, member 1) belongs to the peptidase M14 family. However, no carboxypeptidase activity has yet been detected. It may be involved in cell-cell interactions.Members of the M14 metallocarboxypeptidase protein family serve many diverse functions and are divided into three subfamilies based on structure, function and amino acid sequence similarity. Belonging to the N/E subfamily, CPXM (metallocarboxypeptidase CPX-1) is a 734 amino acid protein that contains a F5/8 type C domain and likely binds one zinc ion per subunit. Most members of the N/E subfamily contain several domains, including an active carboxypeptidase domain and signal peptide, and are thought to function mostly in protein-protein interactions and/or protein-membrane interactions, thereby targeting the protein to specific locations within the secretory pathway. CPXM is a unique member of this subfamily in that it does not appear to exhibit any enzymatic activity due to lack of several active-site residues that are present in the catalytic domain of other members of the N/E subfamily. Studies showing that CPXM expression is regulated during osteoclastogenesis suggest that CPXM may play a role in osteoclast differentiation. There are two isoforms of CPXM which are a result of alternative splicing events.

Supplier: Bioss

Selenium is an essential trace element that confers tolerance to toxicity arising through exposure to heavy metals or other reactive xenobiotics. Selenium exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. Both effects are attributed to selenium-binding proteins. Selenium binding protein 1 is down-regulated in lung adenocarcinoma, colorectal cander and ovarian cancer. It is two-fold upregulated in the brains of patients suffering from schizophrenia, and is therefore a biomarker for this disease.

Supplier: Bioss

Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence. GATA-1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes. It is an essential component in the generation of the erythroid lineage. GATA-2 is expressed in embryonic brain and liver, HeLa and endothelial cells, as well as in erythroid cells. Studies with a modified GATA consensus sequence, AGATCTTA, have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence. This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1. GATA-3 is highly expressed in T lymphocytes. GATA-4, GATA-5 and GATA-6 comprise a subfamily of transcription factors. Both GATA-4 and GATA-6 are found in heart, pancreas and ovary; lung and liver tissues exhibit GATA-6, but not GATA-4 expression. GATA-5 expression has been observed in differentiated heart and gut tissues and is present throughout the course of development in the heart. Although expression patterns of the various GATA transcription factors may overlap, it is not yet apparent how the GATA factors are able to discriminate in binding their appropriate target sites.

Supplier: Bioss

BSX(Brain-specific homeobox protein homolog) may play a role in the determination and function of cell types in the brain. In brain, it is restricted to a few specific developing brain structures such as pineal gland, telencephalic septum, hypothalamic pre-mammillary body and arcuate nucleus. Bsx might be considered an important molecular marker for early embryonic stages of epiphysis development. It belongs to the distal-less homeobox family and contains 1 homeobox DNA-binding domain.

Supplier: Bioss

The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

Supplier: MOINEAU

This small thermo-hygrometer can be used for outdoor and indoor measurements.

Supplier: Thermo Fisher Scientific

Transport cryogenic industrial gases with Thermo Scientific™ LN₂ supply tanks, which are designed to be both durable and user-friendly.

Supplier: IKA

Interchangeable sieve for insertion into the grinding heads ensures maximum particle size filtering.

Supplier: Abcam

Rabbit monoclonal [EPR16848-34] to Leptin - BSA and Azide free.

Supplier: Abcam

Rabbit monoclonal [EPR20756-1] to IL-20 - BSA and Azide free (Capture).

Supplier: Abcam

Rabbit monoclonal [EPR20803-20] to FGF19 - BSA and Azide free (Capture).

Supplier: Abcam

Rabbit monoclonal [EPR23300-33] to SGK1 - BSA and Azide free (Capture).

Supplier: Abcam

Rabbit monoclonal [EPR3821-33] to PCNA - BSA and Azide free (Capture).

Supplier: Abcam

Rabbit monoclonal [EPR25373-32] to CXCR3 - BSA and Azide free.

Supplier: Abcam

Mouse monoclonal [N486/32] to c-Fos - BSA and Azide free.

Supplier: Abcam

Rabbit monoclonal [EPR1622Y] to Cytokeratin 20 - Cytoskeleton Marker.

Supplier: Abcam

Rabbit monoclonal [EPR4513-32-7] to Cdk4.

Supplier: Abcam

Rabbit monoclonal [EPR1114] to IL-10.

Supplier: Abcam

Rabbit monoclonal [EPR23904-20] to FRZB - BSA and Azide free.

Supplier: Abcam

Rabbit monoclonal [EPR23500-32] to SV2A - BSA and Azide free.

Supplier: Abcam

Rabbit monoclonal [EPR15005-34] to FBXO40 - BSA and Azide free.

Supplier: TCI

(Toluene-3,4-dithiolato)zinc(II) ≥95.0% (by titrimetric analysis)

Supplier: TCI

3,5-Di(2-pyridyl)pyrazole ≥98.0% (by GC, titration analysis)

Supplier: US Biological

Anti-Interleukin 10 Receptor alpha Rabbit Polyclonal Antibody