60554 Results for: "3H-Imidazo[4,5-c]pyridine&pageNo=8"
Midostaurin ≥98% (by TLC)
Supplier: Enzo Life Sciences
Inhibitor of a variety of serine/threonine and tyrosine kinases, like protein kinase C (PKC), cyclic AMP-dependent protein kinase (PKA), S6 kinase, Akt (protein kinase B; PKB), epidermal growth factor receptor (EGFR) tyrosine kinase activity and others including KDR, VEGFR, PDGFR, c-kit and other receptor tyrosine kinases. Potently inhibits FLT-3 kinase including mutant forms found in acute myeloid leukemia in vitro and in vivo. Apoptosis inducer. Showed broad antiproliferative activity against various tumor cell lines. Selectively inhibits T lymphocyte production of TNF-α. Upregulates endothelial nitric oxide synthase (eNOS; NOS III). Abrogates tumor angiogenesis in vivo.
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5,8,11,14-Eicosatetraynoic acid ≥98%
Supplier: Enzo Life Sciences
Arachidonic acid uptake inhibitor
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Chaetomellic acid A ≥98% (by TLC)
Supplier: Enzo Life Sciences
Potent inhibitor of farnesyltransferase in isolated enzyme assays (IC50=55nM) but is inactive in whole cells. Inhibition of farnesyltransferase is selective over geranylgeranyltransferase I and II (IC50=92µM and 34µM respectively).
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Lovastatin ≥98% (by TLC)
Supplier: Enzo Life Sciences
HMG-CoA reductase inhibitor
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VWR® Mega Racks® Tube Racks for 28 to 32 mm Tubes
Supplier: VWR Collection
High-capacity storage for 50 ml tubes.
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3,4-Di(1H-indol-3-yl)-1H-pyrrole-2,5-dione ≥98%
Supplier: Enzo Life Sciences
PKC inhibitor
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Rosmarinic acid ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Rosmarinic acid ≥98% (by HPLC)
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(-)-Epigallocatechin gallate ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Inhibitor of NOS, telomerase and Dnmt
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Tryptanthrin ≥98% (by 1H-NMR, HPLC)
Supplier: Enzo Life Sciences
Inhibitor of prostaglandin and leukotriene synthesis.
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Ferutinin ≥98% (by HPLC), white to off-white solid, high purity
Supplier: Enzo Life Sciences
Estrogen receptor α activator.
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BAY 61-3606 hydrochloride ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Syk inhibitor
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Butein ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Tyrosine kinase inhibitor
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Isoxanthohumol ≥98% (by 1H-NMR)
Supplier: Enzo Life Sciences
Phytoestrogen.
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Nourseothricin sulphate (from Streptomyces noursei) ≥85%
Supplier: Enzo Life Sciences
Antibiotic
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Nadifloxacin ≥98%
Supplier: Enzo Life Sciences
Fluoroquinolone with broad spectrum activity against Gram-negative and Gram-positive bacteria. Inhibits the generation of O2- and OH radicals by neutrophils. Inhibits the production of inflammatory cytokines.
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Sparfloxacin ≥98%
Supplier: Enzo Life Sciences
Fluoroquinolone with broad spectrum antibacterial activity against Gram-positive and Gram-negative bacteria. Inhibits bacterial DNA gyrase (topoisomerase). Effective against Mycobacterium tuberculosis. Shows photosensitizing effects.
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Methyl-6-O-(N-heptylcarbamoyl)-α-D-glucopyranoside ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Non-ionic, glucose based very mild detergent for membrane protein purification.
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Gardiquimod ≥98% (by HPLC and UV method)
Supplier: Enzo Life Sciences
TLR7 ligand.
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Purmorphamine ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Smoothened activator.
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Spectinomycin sulphate ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Antibiotic. Inhibits protein synthesis (elongation) by interfering with peptidyl tRNA translocation. Effective against Gram-negative and Gram-positive bacteria (Gonnococcus only). Mutation in rpsE (the gene for ribosomal protein S5) prevents binding of spectinomycin.
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Alamethicin ≥98% (by TLC)
Supplier: Enzo Life Sciences
Mixture of alamethicin homologs. Membrane permeabilizing antibiotic. Applications include increasing [32P] incorporation into phosphatidylinositol 4-phosphate and permeabilization of sarcoplasmic reticulum vesicles. Causes fusion of lipid vesicles.
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Bleomycin sulphate (mixture) ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Anti-tumor agent. Induces apoptosis via DNA damage. Radiomimetic DNA-cleaving agent that produces double and single DNA strand breaks through an oxygen-radical-dependent mechanism. Inhibits intracellular DNA replication. DNA alkylating agent.