141665 Results for: "3\'-Fluoro-4\'-(trifluoromethyl)acetophenone&pageNo=22"

Supplier: Thermo Scientific

Methyl-2,6-dichloro-5-fluoronicotinate

Supplier: Thermo Scientific

2,4-Dichloro-3,5-xylenol

Supplier: Thermo Fisher Scientific

2-Amino-2-methyl-1-propanol buffer, colorless and odorless.

Supplier: Thermo Scientific

6-tert-Butyl-2,4-xylenol

Supplier: LGC Standards PROMOCHEM

Sodium tetraethylborate 20% in THF

Supplier: STEMCELL Technologies

Interleukin 12 (IL-12p70) is a heterodimeric cytokine composed of p35 and p40 subunits. IL-12 is produced by monocytes, macrophages, dendritic cells, neutrophils, and B cells in response to bacterial products and cytokines such as IFN-γ. The IL-12 receptor is expressed on T, NK, and dendritic cells. Upon binding, IL-12 initiates signaling via the JAK/STAT signaling pathway and stimulates NK, B, and T cells to produce IFN-γ (Watford et al.). It also regulates cytokine synthesis, proliferation of T and NK cells, and stimulates differentiation of CD4+ and CD8+ T cells (Germann and Rüde). Mice that are deficient in IL-12 are susceptible to many intracellular pathogens and have impaired IFN-γ secretion, Th1 differentiation, and NK cytolytic activity; however, Th2 development and IL-4 production are enhanced (Watford et al.).

Supplier: Thermo Scientific

4-Amino-N-(2,4-difluorophenyl)benzenesulphonamide

Supplier: LGC Standards PROMOCHEM

2,3,3'-Trichlorobiphenyl (PCB No. 20)

Supplier: Thermo Scientific

2,6-Bis(hydroxymethyl)-p-cresol

Supplier: Restek

This mixture can be used for quantification (AOCS Method CE 1a–13) and approximate the compositions of the types of oils like coconut, palm kernel, babassu, and ouri-curi oil.

Supplier: Thermo Scientific

2,5-Dimethyl-1,3,4-thiadiazole

Supplier: EHRENSTORFER

2,4-Dichloro-3,5-xylenol

Supplier: Spectrum Chemical

Monothioglycerol, NF is a buffering agent excipient. 

Supplier: AccuStandard

2,6-Dichlorobiphenyl (PCB No. 10)

Supplier: Serva

Glutaraldehyde 25% in aqueous solution

Supplier: LGC Standards PROMOCHEM

2,4',6-Trichlorobiphenyl (PCB No. 32)

Supplier: EHRENSTORFER

Dicloran (2,6-dichloro-4-nitroaniline)

Supplier: CELLPATH

21 compartments for 76×26, 50×76 and 76×76 mm slides or 35 mm transparencies with hanging system for storage in conventional filing cabinet.

Supplier: Thermo Scientific

3-Bromo-2,6-dihydroxy-5-nitrobenzonitrile

Supplier: STEMCELL Technologies

Fibroblast growth factor 21 (FGF-21) is a member of the FGF family. Using β-Klotho as a cofactor, FGF-21 signals through FGF receptor 1c and 4 to activate PI3K and MAPK pathways (Mattila and Härkönen; Kharitonenkov et al.). FGF-21 expression is regulated by tissue-specific peroxisome proliferator-activated receptors (PPARs). Upon PPAR-α stimulation FGF-21 is produced in the liver, and activation of PPAR-γ leads to FGF-21 production in adipose tissue. FGF-21 promotes insulin-independent glucose uptake and lipid accumulation in primary human adipocytes and in mouse 3T3-L1 cells. In pancreatic islets and INS-1 cells it inhibits glucose-mediated glucagon release and stimulates insulin production. FGF-21 does not induce proliferation in immortalized cell lines, unlike other FGFs (Kharitonenkov and Shanafelt). FGF-21 regulates thermogenesis in white and brown adipose tissue, and metabolic processes in cells of pancreatic origin (Kharitonenkov et al.).

Supplier: EHRENSTORFER

2,3,3'-Trichlorobiphenyl (PCB No. 20)

Supplier: STEMCELL Technologies

Interleukin 21 (IL-21) is a pleiotropic cytokine that is composed of four α-helical bundles and primarily produced by natural killer T (NKT) cells, T follicular helper (Tfh) cells, and Th17 cells (Spolski and Leonard 2008). IL-21 signals via receptor heterodimerization of IL-21 receptor and IL-2 receptor subunit gamma (IL-2RG or CD132), both of which have a common gamma-chain subunit and activate the JAK/STAT, MAPK, and PI3K pathways (Parrish-Novak et al.; Ozaki et al. 2000; Spolski and Leonard 2014). IL-21 has been shown to have a critical role in regulating immunoglobulin production and differentiation of the pro-inflammatory Th17 population of cells (Ozaki et al. 2002; Nurieva et al.). Additionally, IL-21 specifically sustains CD8+ T cell effector activity and provides a mechanism of CD4+ T cell help during chronic viral infection (Elsaesser et al.). IL-21 signaling was also found critical for the development of type 1 diabetes in non-obese diabetic (NOD) mice (Sutherland et al.) and control of T cell autoimmunity by regulatory B cells (Yoshizaki et al.).

Supplier: BURKLE

Solid sampler, Sealing sleeves, PP, sterilisable, Ø = 25 mm, 150 mm, Ø: 25 mm

Supplier: TCI

3-Chloropyridine N-Oxide ≥98.0% (by GC, titration analysis)

Supplier: Thermo Fisher Scientific

Silver ≥99.9% (metals basis), foil, annealed, Thickness: 0.5 mm (0.02 in)

Supplier: Thermo Fisher Scientific

Lead(II) bromide 98+%, Extra Pure

Supplier: Thermo Fisher Scientific

Imidazole-4,5-dicarboxylic acid 99%

Supplier: Thermo Fisher Scientific

Silver ≥99.9% (metals basis), foil, annealed, Thickness: 1.0 mm (0.04 in)

Supplier: Thermo Fisher Scientific

Fullerene C70 98+%, powder

Supplier: Thermo Fisher Scientific

Silver 99.9%, foil 25x25 mm, Thickness: 1.0 mm , 1ea = 6.6gr