Supplier: Bioss

Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression. Recruitment of SETDB1 induces heterochromatinization. May play a role as a coactivator for CEBPB and NR3C1 in the transcriptional activation of ORM1. Also corepressor for ERBB4. Inhibits E2F1 activity by stimulating E2F1-HDAC1 complex formation and inhibiting E2F1 acetylation. May serve as a partial backup to prevent E2F1-mediated apoptosis in the absence of RB1. Important regulator of CDKN1A/p21(CIP1). Has E3 SUMO-protein ligase activity toward itself via its PHD-type zinc finger. Also specifically sumoylates IRF7, thereby inhibiting its transactivation activity. Ubiquitinates p53/TP53 leading to its proteosomal degradation; the function is enhanced by MAGEC2 and MAGEA2, and possibly MAGEA3 and MAGEA6. Mediates the nuclear localization of KOX1, ZNF268 and ZNF300 transcription factors.

Supplier: Amarell

[EN]HYDROMETER DIN12791 0,60-2,00 1 * 1 ST

Supplier: Pharmablock (USA)

1-(5-BROMO-4-HEXYL-2-THIENYL)-5-METHYL-2 1 * 1 g

Supplier: LIEDER JOHANNES

[EN]MENDELIAN INHERITANCE 32 TRANSPARENC 1 * 32 ST

Supplier: Pharmablock (USA)

TERT-BUTYL (4S)-4-[[(R)-TERT-BUTYLSULFIN 1 * 1 g

Supplier: AMBEED

2-(((9H-FLUOREN-9-YL)METHOXY)CARBONYL)-8 1 * 0,1 g

Supplier: AMBEED

5,5-DIFLUORO-1,3,7,9-TETRAMETHYL-10-PHEN 1 * 1 g

Supplier: LIEDER JOHANNES

[EN]NON-FLOWERING PLANTS, ANATOMY 1 * 1 ST

Supplier: Abnova

CD24 RECOMBINANT PROTEIN (P01) 1 * 1 EA

Supplier: Abnova

APR-2 RECOMBINANT PROTEIN (Q01) 1 * 1 EA

Supplier: Abnova

ST3GAL2 RECOMBINANT PROTEIN (Q01) 1 * 1 EA

Supplier: Abnova

ITGB4 RECOMBINANT PROTEIN (Q01) 1 * 1 EA

Supplier: Abnova

MGST3 RECOMBINANT PROTEIN (Q01) 1 * 1 EA

Supplier: Abnova

GLRA2 RECOMBINANT PROTEIN (P01) 1 * 1 EA

Supplier: Abnova

CYP3A7 RECOMBINANT PROTEIN (Q01) 1 * 1 EA

Supplier: Abnova

HLA-DOA RECOMBINANT PROTEIN (Q01) 1 * 1 EA

Supplier: Abnova

VAMP1 RECOMBINANT PROTEIN (Q01) 1 * 1 EA

Supplier: Bioss

Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression. Recruitment of SETDB1 induces heterochromatinization. May play a role as a coactivator for CEBPB and NR3C1 in the transcriptional activation of ORM1. Also corepressor for ERBB4. Inhibits E2F1 activity by stimulating E2F1-HDAC1 complex formation and inhibiting E2F1 acetylation. May serve as a partial backup to prevent E2F1-mediated apoptosis in the absence of RB1. Important regulator of CDKN1A/p21(CIP1). Has E3 SUMO-protein ligase activity toward itself via its PHD-type zinc finger. Also specifically sumoylates IRF7, thereby inhibiting its transactivation activity. Ubiquitinates p53/TP53 leading to its proteosomal degradation; the function is enhanced by MAGEC2 and MAGEA2, and possibly MAGEA3 and MAGEA6. Mediates the nuclear localization of KOX1, ZNF268 and ZNF300 transcription factors.

Supplier: Bioss

Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression. Recruitment of SETDB1 induces heterochromatinization. May play a role as a coactivator for CEBPB and NR3C1 in the transcriptional activation of ORM1. Also corepressor for ERBB4. Inhibits E2F1 activity by stimulating E2F1-HDAC1 complex formation and inhibiting E2F1 acetylation. May serve as a partial backup to prevent E2F1-mediated apoptosis in the absence of RB1. Important regulator of CDKN1A/p21(CIP1). Has E3 SUMO-protein ligase activity toward itself via its PHD-type zinc finger. Also specifically sumoylates IRF7, thereby inhibiting its transactivation activity. Ubiquitinates p53/TP53 leading to its proteosomal degradation; the function is enhanced by MAGEC2 and MAGEA2, and possibly MAGEA3 and MAGEA6. Mediates the nuclear localization of KOX1, ZNF268 and ZNF300 transcription factors.

Supplier: Bioss

Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression. Recruitment of SETDB1 induces heterochromatinization. May play a role as a coactivator for CEBPB and NR3C1 in the transcriptional activation of ORM1. Also corepressor for ERBB4. Inhibits E2F1 activity by stimulating E2F1-HDAC1 complex formation and inhibiting E2F1 acetylation. May serve as a partial backup to prevent E2F1-mediated apoptosis in the absence of RB1. Important regulator of CDKN1A/p21(CIP1). Has E3 SUMO-protein ligase activity toward itself via its PHD-type zinc finger. Also specifically sumoylates IRF7, thereby inhibiting its transactivation activity. Ubiquitinates p53/TP53 leading to its proteosomal degradation; the function is enhanced by MAGEC2 and MAGEA2, and possibly MAGEA3 and MAGEA6. Mediates the nuclear localization of KOX1, ZNF268 and ZNF300 transcription factors.

Supplier: Santa Cruz Biotechnology

RAMP2 (B-5) 1 * 1 EA

Supplier: Bohlender

[EN]GUIDE SLEEVE NS29/32 Ø8 + 10MM 1 * 1 ST

Supplier: CUSTOM MADE CHEMICALS LAB

[EN]BDE 206 1 * 1 mL

Supplier: Chemicon

CONNEXIN 32 [GAP JUNCTION BETA-1 PROTEIN 1 * 1 EA

Supplier: SCHUELKE MAYR

[EN]DISINFECTANT WIPES SCHÜLKE WIPES 100 1 * 6 ST

Supplier: Abnova

NUCB1 RECOMBINANT PROTEIN (P01) 1 * 1 EA

Supplier: Abnova

GAGE5 RECOMBINANT PROTEIN (Q01) 1 * 1 EA

Supplier: Abnova

IFNAR1 RECOMBINANT PROTEIN (Q01) 1 * 1 EA

Supplier: Abnova

NOG RECOMBINANT PROTEIN (P01) 1 * 1 EA

Supplier: Abnova

ECHS1 RECOMBINANT PROTEIN (Q01) 1 * 1 EA