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Human recombinant HES1 (from E. coli)

Supplier: ProSci Inc.

bHLH proteins are essential for neurogenesis, myogenesis, haematopoiesis and sex determination. HES1 (Hairy and Enhancer of Split 1) is a basic Helix-Loop-Helix (bHLH) transcriptional repressor regulated by the Notch pathway and expressed in various tissues. HES1 is well known in development of different tissues, particularly endoderm derived endocrine organs like pancreas and neuroendocrine cells of lung. HES1 controls normal development by regulating proliferation and differentiation and so cell fate. Notch signalling plays both oncogenic and tumour suppressor roles depending on cell type. In contrast to T cell acute lymphoblastic leukaemia (ALL), where Notch activation promotes leukemogenesis, induction of Notch signalling in B cell ALL (B-ALL) leads to growth arrest and apoptosis. The Notch target HES1 is sufficient to reproduce this tumour suppressor phenotype in B-ALL by interacting and activating PARP-1 and regulating proapoptotic signals.

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Anti-ZIP2 Rabbit Polyclonal Antibody

Anti-ZIP2 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

ZIP2 Antibody: The zinc transporter ZIP2, also known as SLC39A2, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Similar to knock-outs of ZIP1 and ZIP3, ZIP2-null mice have no phenotypic differences compared to wild-type mice. Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient. More recent studies have shown that ZIP2 and ZIP3 are down regulated in human prostate adenocarcinomatous glands, and may be important in the retention of zinc in the cellular compartment.

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Trousers, Fristads® PR54-220, Design B, black

Trousers, Fristads® PR54-220, Design B, black

Supplier: FRISTADS KANSAS

Thanks to their durability and comfort, these trousers are perfectly suitable for use in garages as well as in industrial and service companies. The material is made of 65% polyester and 35% cotton. The inside is brushed and provides a comfortable cotton feel. The outside is very hardwearing and does not bleach, even after countless washes.

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Anti-RNF39 Rabbit Polyclonal Antibody

Anti-RNF39 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

Its gene lies within the major histocompatibility complex class I region on chromosome 6. Studies of a similar rat protein suggest that RNF39 plays a role in an early phase of synaptic plasticity. Its gene lies within the major histocompatibility complex class I region on chromosome 6.This gene lies within the major histocompatibility complex class I region on chromosome 6. Studies of a similar rat protein suggest that this gene encodes a protein that plays a role in an early phase of synaptic plasticity. Alternative splicing results in three transcript variants encoding different isoforms.This gene lies within the major histocompatibility complex class I region on chromosome 6. Studies of a similar rat protein suggest that this gene encodes a protein that plays a role in an early phase of synaptic plasticity. Alternative splicing results in three transcript variants encoding different isoforms.

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Trousers, Fristads® PR54-220, Design B, Navy blue

Trousers, Fristads® PR54-220, Design B, Navy blue

Supplier: FRISTADS KANSAS

Thanks to their durability and comfort, these trousers are perfectly suitable for use in garages as well as in industrial and service companies. The material is made of 65% polyester and 35% cotton. The inside is brushed and provides a comfortable cotton feel. The outside is very hardwearing and does not bleach, even after countless washes.

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Anti-ZIP3 Rabbit Polyclonal Antibody

Anti-ZIP3 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

ZIP3 Antibody: The zinc transporter ZIP3, also known as SLC39A3, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Similar to knock-outs of ZIP1 and ZIP2, ZIP3-null mice have no phenotypic differences compared to wild-type mice. Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient. More recent studies have shown that ZIP2 and ZIP3 are down regulated in human prostate adenocarcinomatous glands, and may be important in the retention of zinc in the cellular compartment.

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PIG® universal mat rolls

PIG® universal mat rolls

Supplier: NEW PIG

Eight layers of 100% PP are thermally bonded to make PIG Mat exceptionally strong; won't rip, tear or fray even when saturated.

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Trousers, Fristads® PR54-220, Design A, royal blue

Trousers, Fristads® PR54-220, Design A, royal blue

Supplier: FRISTADS KANSAS

Thanks to their durability and comfort, these trousers are perfectly suitable for use in garages as well as in industrial and service companies. The material is made of 65% polyester and 35% cotton. The inside is brushed and provides a comfortable cotton feel. The outside is very hardwearing and does not bleach, even after countless washes.

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Pilot's jacket, Icon

Pilot's jacket, Icon

Supplier: FRISTADS KANSAS

Functional, two-tone winter jacket made from Beaver nylon (50% nylon, 50% cotton), a hard-wearing and tear-proof material that is resistant to dirt, oil and water. With faux fur on the collar and on the body, quilted lining in the sleeves and contrasting seams.

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VWR® Incubating Mini Shaker, 230 V

VWR® Incubating Mini Shaker, 230 V

Supplier: VWR Collection

VWR® Incubating mini shakers feature variable-speed, microprocessor control, providing reliable, uniform mixing action with accurate temperature control. Ideal for cell cultures, solubility studies, extraction procedures, diagnostic tests, general mixing, hybridisation, genetics research, bacterial suspensions, staining/destaining and washing procedures.

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Masterflex® Ismatec® Reglo Digital Miniflex Pumps, Avantor®

Masterflex® Ismatec® Reglo Digital Miniflex Pumps, Avantor®

Supplier: Avantor Fluid Handling

Versatile pumps for accurate low-flow fluid delivery – with an intuitive touch-screen interface.

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DUNKELKAMMER CM-10 1 * 1 ST

Supplier: MARKET SOURCE PART PROCESS

DUNKELKAMMER CM-10 1 * 1 ST

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PIG® HazMat absorbent pillows

PIG® HazMat absorbent pillows

Supplier: NEW PIG

High capacity pillows pump up the absorbing power on large spills of corrosive liquids.

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VWR® VisiScope® TL534B FL4, Fluorescence Microscopes

VWR® VisiScope® TL534B FL4, Fluorescence Microscopes

Supplier: VWR Collection

Advanced routine fluorescence microscope for transmitted brightfield and fluorescence observations with high quality IOS W-Plan or IOS W-Plan F (Semi-Apo) objectives. Suitable for educational and laboratory applications.

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Sharpsafe® Ecological 5th Generation Recycled Needle Containers

Sharpsafe® Ecological 5th Generation Recycled Needle Containers

Supplier: Hospidex

Sharpsafe®, historic pioneer in protecting against the risk of sharps injuries and sustainability in medical waste packaging management, presents the recycled 5th generation needle containers.

    
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ESD Safety Shoes, Low, Red, IAN XXTP, S2

Supplier: ELTEN

Unisex IAN XXTP red Low ESD S2 safety shoes with excellent wearing comfort where the padded upper edge protects the Achilles tendon. The tongue prevents pressure marks and avoids dirt from entering into the shoe. The shoes gives  a good visibility in the dark.

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VWR® Visiscope® IT407 FL Inverted Trinocular Fluorescence Microscopes

VWR® Visiscope® IT407 FL Inverted Trinocular Fluorescence Microscopes

Supplier: VWR Collection

Routine inverted fluorescence microscopes for transmitted brightfield, phase contrast (optional for IT407 FL4 and IT407 FLD4 FLD) and fluorescence observations with IOS LWD W-Plan PH or U-Plan F objectives. Ideal for tissue culture research in clinical and biotechnology laboratories.

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Gas Washing Bottle 250 ml, Head with VitraPOR® Filter Disc, Standard Joint NS 29/32

Gas Washing Bottle 250 ml, Head with VitraPOR® Filter Disc, Standard Joint NS 29/32

Supplier: ROBU GLASFILTER

ROBU® gas washing bottle head with integrated VitraPOR® filter disc and standard ground joint ensures efficient gas-liquid contact and uniform dispersion in absorption processes.

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Storage tubes, 2D barcoded, Matrix™

Storage tubes, 2D barcoded, Matrix™

Supplier: THERMO MATRIX TECHNOLOGIES

Permanently attached, laser-etched 2D barcodes on the bottom of each tube allow you to scan and decode tubes at once without removing them from the rack and allow data to be associated with each tube.

    
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Trousers, Fristads® PR54-220, Design B, dark grey

Trousers, Fristads® PR54-220, Design B, dark grey

Supplier: FRISTADS KANSAS

Thanks to their durability and comfort, these trousers are perfectly suitable for use in garages as well as in industrial and service companies. The material is made of 65% polyester and 35% cotton. The inside is brushed and provides a comfortable cotton feel. The outside is very hardwearing and does not bleach, even after countless washes.

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Robotic tips (CO-RE Tips) and consumables for Microlab

Robotic tips (CO-RE Tips) and consumables for Microlab

Supplier: HAMILTON ROBOTICS

Hamilton CO-RE tips were designed for MICROLAB pipetting workstations in order to solve the problem of sealing and alignment plagued by press-fit tip attachment techniques. Each CO-RE disposable tip has a circular groove inside the attachment orifice. An o-ring on the pipetting channel is expanded to fit this groove precisely providing an air-tight seal and straight alignment between tip and pipetting channel.

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Industrial jacket, Fristads® PR54-420, design B, black

Industrial jacket, Fristads® PR54-420, design B, black

Supplier: FRISTADS KANSAS

Thanks to its durability and high degree of comfort, the PR54 jacket is perfectly suited to workshops and industrial and service enterprises. The material is made from 65% polyester and 35% cotton. The inside is brushed and as a result conveys a pleasantly comfortably cotton feeling. The outside is also resistant to the roughest demands and will not fade even after countless washes.

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Overall, C.I., Design B, black

Supplier: FRISTADS KANSAS

Industrial overall made of 65% polyester and 35% cotton, with soft nap on reverse side. The black overall is available with several different accent colours. The accent colour can be found on the top of the collar, on the inside front flap, on the pocket edges and and as a stripe on front and back.

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Trousers, Fristads® PR54-220, Design A, dark grey

Trousers, Fristads® PR54-220, Design A, dark grey

Supplier: FRISTADS KANSAS

Thanks to their durability and comfort, these trousers are perfectly suitable for use in garages as well as in industrial and service companies. The material is made of 65% polyester and 35% cotton. The inside is brushed and provides a comfortable cotton feel. The outside is very hardwearing and does not bleach, even after countless washes.

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Porte vitrée avec éclairage par led pour 1300LX 1 * 1 Pce

Supplier: GETINGE LIFE SCIENCES

Porte vitrée avec éclairage par led pour 1300LX 1 * 1 Pce

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VOLLBLICKMASKE 1 * 1 ST

Supplier: Roth Carl

VOLLBLICKMASKE 1 * 1 ST

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Test tube,AF215TT with stopper for use with DB415,Lovibond 1 * 1 items

Supplier: Lovibond Tintometer

Test tube,AF215TT with stopper for use with DB415,Lovibond 1 * 1 items

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Overalls with Bib and Braces, Fristads® PR54-22 Design B, black

Overalls with Bib and Braces, Fristads® PR54-22 Design B, black

Supplier: FRISTADS KANSAS

Thanks to their durability and comfort, these trousers are perfectly suited to workshops, and industrial and service enterprises. The material is made from 65% polyester and 35% cotton. The inside is brushed, ensuring a pleasantly comfortable cotton feel. The outside can withstand the roughest demands and will not fade, even after countless washes.

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Industrial jacket, Fristads® PR54-420, design B, navy blue

Industrial jacket, Fristads® PR54-420, design B, navy blue

Supplier: FRISTADS KANSAS

Thanks to its durability and high degree of comfort, the PR54 jacket is perfectly suited to workshops and industrial and service enterprises. The material is made from 65% polyester and 35% cotton. The inside is brushed and as a result conveys a pleasantly comfortably cotton feeling. The outside is also resistant to the roughest demands and will not fade even after countless washes.

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VWR® Classic LP / LPC / LPW, Precision Balances with LCD

VWR® Classic LP / LPC / LPW, Precision Balances with LCD

Supplier: VWR Collection

Rugged and economical balances, that are ideal for educational establishments and laboratory use. A series that ranges from simple weighing to operation with automated internal calibration. All Classic models have a simple backlit LCD with adjustable contrast and ergonomic keypad and a stainless steel top pan.

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