28093 Results for: "2,2-Diphenyl-1-picrylhydrazyl+(free+radical)&pageNo=77"

Supplier: Abcam

APC Rat monoclonal [53-7.3] to CD5.

Supplier: US Biological

Anti-Glucose Regulated Protein 78 Rabbit Polyclonal Antibody

Supplier: US Biological

Anti-MAP2 Mouse Monoclonal Antibody [clone: MT-07]

Supplier: Apollo Scientific

Methyl 5,7-dichloro[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxylate

Supplier: Abcam

Rabbit monoclonal [73-10] to PD-L1.

Supplier: TCI

2,3-Dibromo-6,7-dicyanonaphthalene ≥98.0% (by HPLC, total nitrogen)

Supplier: Abcam

PerCP/Cy5.5® Rat monoclonal [M1/70] to CD11b.

Supplier: Tonbo Biosciences

The 53-6.7 antibody reacts with the 32-34 kDa alpha subunit of mouse CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor in antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.

Supplier: US Biological

Anti-ITGAM Rat Monoclonal Antibody [clone: M1/70]

Supplier: US Biological

Anti-CD8A Mouse Monoclonal Antibody [clone: 53-6.7]

Supplier: US Biological

Anti-Enterovirus 71 Mouse Monoclonal Antibody [clone: 13F54]

Supplier: US Biological

Anti-ABCC11 Rat Monoclonal Antibody [clone: M8I-74]

Supplier: Thermo Fisher Scientific

Diammonium tetrachloropalladate ≥99.998% (metals basis) Pd 37%, Premion®

Supplier: Bioworld Technology

Synthetic peptide, corresponding to amino acids 560-600 of Human Ku-70.

Supplier: Bioworld Technology

Synthetic peptide, corresponding to amino acids 30-84 of Human Bcl-7a.

Supplier: Thermo Fisher Scientific

Nickel (II) oxide, black (≥76% Ni) (contains Ni2O3)

Supplier: TCI

2,7-Dibromo-9,9'-spirobifluorene ≥98.0% (by HPLC, titration analysis)

Supplier: Abcam

Mouse monoclonal [MC813-70] to SSEA4.

Supplier: Abcam

Mouse monoclonal [10F0] to Enterovirus 71.

Supplier: Abcam

PE Rabbit monoclonal [EPR22178-17] to OTP.

Supplier: Abcam

PE Rabbit monoclonal [EPR23554-71] to SIK3.

Supplier: Apollo Scientific

Human Recombinant Peroxisome Proliferator Activated Receptor Gamma (1-477)

Supplier: Bioworld Technology

Synthetic peptide, corresponding to amino acids 100-150 of Human SLP-76.

Supplier: US Biological

Anti-Interleukin 27 Receptor alpha Rabbit Polyclonal Antibody

Supplier: Abcam

Anti-Cytokeratin 7+17 Mouse Monoclonal Antibody [clone: C-46]

Supplier: Biosensis

The heat shock proteins were discovered, as the name suggests, since they are heavily upregulated when cells are stressed by temperatures above the normal physiological range. They are expressed in unstressed cells also and have a normal function as chaperones, helping other proteins to fold correctly, and are required in much greater amounts if the cell or tissue is stressed by heat. The increased levels are generated transcriptionally under the influence of a powerful transcription factor, the heat shock factor 1 (HSF1). The different heat shock proteins were originally named based on their SDS-PAGE mobility, so HSP27 has an apparent molecular weight of 27kDa. It is an abundant protein even under non-stress conditions and frequently shows up as a major spot on 2 dimensional gels of cells or tissues. It is known to associate with a variety of other proteins such as actin, intermediate filament subunits and ubiquitin and is found both in the cytoplasm and the nucleus of cells. HSP27 can become heavily phosphorylated under the influence of multiple protein kinases particularly as a result of activation of the p38/SAPK pathway. Upregulation of this protein is protective against neurodegenerative diseases at least in certain mouse models (1). Point mutations in the HSP27 gene are associated with two neurological diseases, Charcot-Marie-Tooth disease type 2F and distal hereditary motor neuropathy IIB (2). These diseases are associated with axonal loss apparently following defects in the transport of neurofilaments.

Supplier: Biotium

This MAb reacts with a CD32 (FcgRII) epitope (cluster-4). It displays a stronger reaction with Daudi than with U937 cells. The epitope is located in domain 2 of FcgRIIa. Its Fab'2 fragments block immune complex binding. CD32 (FcgRII) is a type 1 transmembrane glycoprotein that mediates several functions including phagocytosis, cytotoxicity, and immunomodulation as well as platelet aggregation. Three genes (A, B, and C) encode CD32 and at least 6 isoforms are generated via alternative mRNA splicing, i.e., IIa1, IIa2, IIb1, IIb2, IIb3 and IIc. Monocytes/macrophages, placental trophoblasts and endothelial cells express all isoforms. In addition, the IIb isoform is expressed by B cells, and the IIa isoform by platelets, granulocytes and, weakly, by B cells. NK cells and neutrophils express Isoform IIc. CD32 binds weakly to the Fc region of monomeric IgG but more strongly to IgG aggregates and immune complexes.

Supplier: TCI

4,7-Bis(5-trimethylstannyl-2-thienyl)-2,1,3-benzothiadiazole ≥95.0% (by GC)

Supplier: Biotium

ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This MAb is specific to Synacthen (aa1-24 of ACTH); does not react with CLIP (aa17-39 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs).It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH.

Supplier: Biotium

ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This MAb is specific to Synacthen (aa1-24 of ACTH); does not react with CLIP (aa17-39 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs).It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH.