62575 Results for: "1-Chloro-2-naphthol&pageNo=50&view=easy"

Supplier: Roth Carl

SILICONPASTE HOCHVISKOS 35G 1 * 35 g

Supplier: witeg Labortechnik

Tubing threaded 46x130x2.3mm gl50 with screw threaded, straight,acc. to din 12216, with iso screw thread,made of borosilicate glass , available with screw thread gl, rd or svl null

Supplier: witeg Labortechnik

Flask for collecting 50ml,with cylindrical stopcock, 145x32mmmm, st14/23, acc. to schlenk, null

Supplier: MARIENFELD

MICROSLIDE HISTOBOND FROST END 76X51MM 1 * 2.250 items

Supplier: witeg Labortechnik

Flask for collecting nitrogen 50ml, 145x32mm, st14/23,acc. to schlenk, null

Supplier: QIAGEN

Vakuum-Pumpe 1 * 1 items

Supplier: Epredia

Microslide superfrost cut blue glass cello ISO 8037/1 1,0mm 1 * 2.000 items

Supplier: PURITAN MEDICAL

SWAB NON ST FOAM TIP HANDLE 6CM 1 * 1.000 items

Supplier: witeg Labortechnik

Flask for collecting 50ml, with cylindrical hook,145x32mmmm,st14/23, acc. to schlenk, null

Supplier: ALPHAG

SCHROEFPOT 50ML BRUIN DIN40 1 * 85 Pce

Supplier: Hielscher Ultrasonics

ULTRASCHALLPROZESSOR UP50H 1 * 1 ST

Supplier: VELP SCIENTIFIC

The OHS Series overhead stirrers are the ideal solution for the most demanding applications: The powerful brushless motor and microprocessor ensure excellent performance and make the VELP OHS Series overhead stirrers unlike any conventional stirrer.

Supplier: witeg Labortechnik

Flask, 50ml, ST19/26, pear shaped, outer diameter 51mm, height 105mm, borosilicate glass 3.3 1 * 1 items

Supplier: Greisinger

PT 100 IMMERSION PROBE FOR LIQUIDS/GASES 1 * 1 items

Supplier: Nitritex

FACE VEIL WITH STUDS MICROFLOW BIOCLEAN 1 * 500 items

Supplier: witeg Labortechnik

Flask, 50ml, ST14/23, pear shaped, outer diameter 51mm, height 100mm, borosilicate glass 3.3 1 * 1 items

Supplier: MACHEREY-NAGEL

Filter paper circles MN 614 50cm diameter, pack of 100. 1 * 100 items

Supplier: ProSci Inc.

The Fas is also known as FAS receptor (FasR), apoptosis antigen 1 (APO-1 or APT), cluster of differentiation 95 (CD95) or tumor necrosis factor receptor superfamily member 6 (TNFRSF6). is a death receptor on the surface of cells that leads to programmed cell death (apoptosis). It is one of two apoptosis pathways, the other being the mitochondrial pathway. FasR is located on chromosome 10 in humans and 19 in mice. Similar sequences related by evolution (orthologs) are found in most mammals. Fas forms the death-inducing signaling complex (DISC) upon ligand binding. Membrane-anchored Fas ligand trimer on the surface of an adjacent cell causes trimerization of Fas receptor. This event is also mimicked by binding of an agonistic Fas antibody, though some evidence suggests that the apoptotic signal induced by the antibody is unreliable in the study of Fas signaling. To this end, several clever ways of trimerizing the antibody for in vitro research have been employed.Upon ensuing death domain (DD) aggregation, the receptor complex is internalized via the cellular endosomal machinery. This allows the adaptor molecule FADD to bind the death domain of Fas through its own death domain. Recently, Fas has also been shown to promote tumor growth, since during tumor progression, it is frequently downregulated or cells are rendered apoptosis resistant. Cancer cells in general, regardless of their Fas apoptosis sensitivity, depend on constitutive activity of Fas. This is stimulated by cancer-produced Fas ligand for optimal growth.

Supplier: STEMCELL Technologies

The B18R protein, which is encoded by the B18R open reading frame in the Western Reserve (WR) strain of vaccinia virus, is a type I interferon (IFN)-binding protein that is known to inhibit IFN antiviral response (Colamonici et al.). B18R protein has been shown to exhibit neutralizing activity to type I interferon family members (Meyers et al.) and to protect cells from the antiviral effects of interferon (Vancová et al.). It was recently shown that HIV-1–dependent induction of type I IFN activity and BAFF protein levels was abrogated by the soluble B18R protein, with no effect observed on the cell viability (Gomez et al.). B18R protein has been reported to aid in cellular reprogramming using RNA-mediated gene delivery (Warren et al.; Yoshioka N et al.).

Supplier: ProSci Inc.

tumour Necrosis Factor- alpha (TNF- alpha) is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells following stimulation by bacterial LPS. Cells expressing CD4 secrete TNF- alpha while cells that express CD8 secrete little or no TNF- alpha. Synthesis of TNF- alpha can be induced by many different stimuli including interferons, IL2, and GM-CSF. The clinical use of the potent anti-tumour activity of TNF- alpha has been limited by the proinflammatory side effects such as fever, dose-limiting hypotension, hepatotoxicity, intravascular thrombosis, and hemorrhage. Designing clinically applicable TNF- alpha mutants with low systemic toxicity has been of intense pharmacological interest. Human TNF- alpha that binds to murine TNF-R55 but not murine TNF-R7, exhibits retained anti-tumour activity and reduced systemic toxicity in mice compared with murine TNF- alpha, which binds to both murine TNF receptors. Based on these results, many TNF- alpha mutants that selectively bind to TNF-R55 have been designed. These mutants displayed cytotoxic activities on tumour cell lines in vitro and have exhibited lower systemic toxicity in vivo. Recombinant Human TNF- alpha High Active Mutant differs from the wild-type by amino acid subsitution of amino acids 1-7 with Arg8, Lys9, Arg10 and Phe157. This mutant form has been shown to have increased activity with less inflammatory side effects in vivo.

Supplier: STEMCELL Technologies

Fibroblast growth factor 8A (FGF-8A) is a member of the fibroblast growth factor (FGF) family and is an isoform of FGF-8. FGF-8A binds the FGF receptor (FGFR) and activates Ras/MAPK signaling (Hulstrand and Houston). The FGF family possesses broad mitogenic and cell survival activities (Folkman and Klagsbrun; Kimelman and Kirschner) and is involved in a variety of biological processes, including cell proliferation, differentiation, survival, and apoptosis (Folkman and Klagsbrun; Klagsbrun; Rifkin and Moscatelli). FGF-8 RNA is spliced to produce 4 protein isoforms in humans: FGF-8A, FGF-8B, FGF-8E, and FGF-8F. The functional differences are not fully understood; however, studies in zebrafish and Xenopus show that FGF-8A is required for endoderm morphogenesis and neurogenesis (Choe and Crump; Hulstrand and Houston).

Supplier: STEMCELL Technologies

R-Spondin-3 is a member of thrombospondin type 1 repeat (TSR-1) superfamily that is involved in the canonical Wnt/β-catenin signaling pathway (de Lau et al.). R-spondin proteins are characterized by two furin-like repeats at the amino terminus and thrombospondin domain located near the carboxyl terminus (de Lau et al.). R-spondin-3 expression is associated with ovarian cancer (Gu et al.), prostate cancer (Mesci et al.), and differentiation of intestinal epithelial cells in diabetes mellitus (Shan et al.). In a transgenic mice model, the expression of R-Spondin-3 induces the expansion of Lgr5+ stem cells, Paneth cells, and Lgr4+ cells, promoting the intestinal stem cell compartment (Hilkens et al.). This protein contains a His-residue tag at the carboxyl end of the polypeptide chain.

Supplier: Roth Carl

STANDBALLON 10L MIT HAHN 1ST 1 * 1 ST

Supplier: MORGAN ADVANCED MATERIALS HALD

ALSINT TILES SQUARE 50X50X4MM 1 * 1 items

Supplier: LAUDA

THERMOMETER RESISTANCE PLATINUM PT 500 1 * 1 items

Supplier: Epredia

Microslide superfrost cut yellow glass cello ISO 8037/1 1,0mm 1 * 2.000 items

Supplier: Epredia

Microslide superfrost cut pink glass cello ISO 8037/1 1,0mm 1 * 2.000 items

Supplier: Roth Carl

SEKUROKA-KÄLTEHANDSCHUH ICE-GRIP, 1PA 1 * 1 PAAR

Supplier: DAKLAPACK

BUBBLE ENVELOP UN3373-ENG 1 * 100 items

Supplier: BIO RAD

[EN]IQ MULTIPLEX POWERMIX 200 REACTIONS