This software is capable of developing and optimising HPLC methods automatically within just a few hours. Methods already in use can also be optimised, thus reducing analysis time considerably. All to do is place the sample in the autosampler, set a few parameters and start the optimisation process. ChromSword Auto® then predicts the method conditions and controls the HPLC system connected in recording the chromatograms.

• Separation of more substances and also with lowest concentrations of impurities (>50 peaks, <0,05%)
• Better peak resolution - therefore, higher degree of robustness and hence more reliable
• Faster separations, shorter analysis times
• Savings in time and effort in method development (automatic optimisation overnight)
• Savings of solvents in method development and routine analysis (cost, disposal, protection of the environment)
• Compatible with a variety of HPLC systems from different manufacturers
• Amortisation of software costs after only few method optimisation runs

These are analysed by the software and the optimal conditions determined. The rapid optimisation mode can be used to provide an overview of the performance of the column/solvent system selected, or to rapidly screen columns and eluents considered for use. The fine optimisation mode additionally collects and evaluates further ancillary data and produces up to 10 sets of alternative optimal HPLC conditions. Both of these operating modes can be applied in combination with column- and solving-switching procedures in order to try a variety of column/solvent combinations, or to establish optimal pH conditions automatically.

For further information on ChromSword Auto® software please contact our specialists at Avantor or email chromatography @eu.vwr.com.

The unique ChromSword Auto® software is capable of developing and optimising HPLC methods fully automatically within just a few hours. Methods already in use can also be optimised, thus reducing analysis time considerably. All you have to do is place the sample in the Autosampler, set a few parameters and start the optimisation process. ChromSword Auto® then predicts the method conditions and controls the HPLC system connected in recording the chromatograms. These are analysed by the software and the optimal conditions determined. The rapid optimisation mode can be used to provide an overview of the performance of the column/solvent system selected or to rapidly screen columns and eluents considered for use. The fine optimisation mode additionally collects and evaluates further ancillary data and produces up to 10 sets of alternative optimal HPLC conditions. Both of these operating modes can be applied in combination with column and solving switching procedures in order to try a variety of column/solvent combinations or to establish optimal pH conditions – fully automatically.

For further information on ChromSword® and ChromSword Auto® software please contact our specialists at VWR or email [email protected].