Human/Mouse/Rat Recombinant GDF-11 (Animal free) (from E. coli)

Growth differentiation factor 11 (GDF-11), also known as bone morphogenetic protein 11 (BMP-11), is a regulator of cell growth and differentiation during muscular and neural development. GDF-11 binds the transforming growth factor-beta receptors ALK4, ALK5, and ALK7 to activate SMAD signaling. In adults, exogenous GDF-11 promotes cardiomyocyte regeneration to reverse age-related cardiac hypertrophy.

High Quality
Low Endotoxin
Affordable

: For research use only.

Conjugation:
Unconjugated
Protein function:
Cytokine
Protein/peptide type:
Recombinant
Source:
E. coli
Species:
Human
Rat
Mouse
Storage conditions:
At or below –20 °C
Endotoxin content:
Endotoxin LAL (EU/µg) ≤0,1
Biological activity:
Bioactivity assay: Alkaline phosphatase activity in ATDC5 cells, ED50 ≤100 ng/ml, Bioactivity ≥1,0×10⁴ units/mg
Gene ID:
O95390 / Q9Z1W4 / Q9Z217
Reconstitution instructions:
Sterile 10 mM HCl at 0.1 mg/ml
Endotoxin-free:
N
Carrier-free:
Y
Protease-free:
N
Animal-free:
Y
Protein synonyms:
BMP-11
Protein/peptide name:
GDF-11
Purity:
≥95%
Molecular weight:
12,5/24,9 kDa
Sequence:
NLGLDCDEHS SESRCCRYPL TVDFEAFGWD WIIAPKRYKA NYCSGQCEYM FMQKYPHTHL VQQANPRGSA GPCCTPTKMS PINMLYFNDK QQIIYGKIPG MVVDRCGCS
Endotoxin level:
Low
Formulation:
0,1% Trifluoroacetic Acid (TFA)
Nuclease-free:
N
Grade:
RUO
Shipping temperature:
RT
Tested applications:
Bioassay