Human Recombinant IL-21 (CTGrade GMP) (from E. coli)

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New Product

About this item

PDGF-BB (Platelet-derived growth factor) comprises a family of homo or heterodimeric growth factors, including PDGF-AA, PDGF-BB, PDGF-CC, and PDGF-DD. Binds to two different transmembrane tyrosine kinase receptors (PDGFR-alpha and PDFGR-beta). Released from degranulating platelets and plays a role in each stage of wound healing. Stimulates mitogenicity and chemotaxis of neutrophils, macrophages, fibroblasts, and smooth muscle cells to the wound site.

High quality
Low endotoxin
Lot-to-lot consistency
Animal free
Manufactured following GMP guidelines

Enhances proliferation of fibroblasts and their production of extracellular matrix. The biological activity of CTGrade GMP interleukins and growth factors is standardized, where applicable, to WHO International standards, providing cell and gene therapy developers consistent, lot-to-lot biological activity and performance.

Host cell protein: ≤30 ng/ml
Host cell DNA: ≤0,01 ng/ml
Sterility testing: No growth
Mycoplasma: Negative

Caution: For research use or further manufacturing only.

Specifications

Conjugation:
Unconjugated
Protein function:
Cytokine
Protein/peptide type:
Recombinant
Source:
E. coli
Species:
Human
Storage conditions:
At or below −20 °C
Endotoxin content:
Endotoxin LAL (EU/µg) ≤0.05
Biological activity:
Bioactivity assay: Proliferation of B9 cell, ED50 ≤5 ng/ml, bioactivity ≥WHO standard not available
Gene ID:
Q9HBE4
Reconstitution instructions:
Sterile water at 0,1 - 0,5 mg/ml
Endotoxin-free:
N
Carrier-free:
Y
Protease-free:
N
Animal-free:
Y
Purity:
≥97%
Molecular weight:
15,4 kDa
Sequence:
MQDRHMIRMR QLIDIVDQLK NYVNDLVPEF LPAPEDVETN CEWSAFSCFQ KAQLKSANTG NNERIINVSI KKLKRKPPST NAGRRQKHRL TCPSCDSYEK KPPKEFLERF KSLLQKMIHQ HLSSRTHGSE DS
Endotoxin level:
Low
Formulation:
10 mM sodium phosphate, pH 7,5
Nuclease-free:
N
Grade:
GMP
Shipping temperature:
Ambient
Tested applications:
Bioassay