Human Recombinant SCF (CTGrade GMP) (from E. coli)

New Product

Human Recombinant SCF (CTGrade GMP) (from E. coli)

New Product

SCF is a multipotent factor which affects cells of the myeloid, erythroid, mast, and lymphoid lineages.

High quality
Low endotoxin
Lot-to-lot consistency
Animal free
Manufactured following GMP guidelines

Exists both as a membrane-bound and soluble form
Expressed by fibroblasts and endothelial cells promoting proliferation, migration, survival, and differentiation in hematopoietic progenitors, melanocytes, and germ cells
Promotes mast cell secretory function, chemotaxis, and adhesion
Enhances secretion of mediators in response to IgE-dependent activation
The biological activity of CTGrade GMP interleukins and growth factors is standardised, where applicable, to WHO International standards, providing cell and gene therapy developers consistent, lot-to-lot biological activity and performance

Host Cell Protein: ≤30 ng/ml
Host Cell DNA: ≤0,01 ng/ml
Sterility testing: No Growth
Mycoplasma: Negative

: For research use or further manufacturing only.

Conjugation:
Unconjugated
Protein function:
Cytokine
Protein/peptide type:
Recombinant
Source:
E. coli
Species:
Human
Storage conditions:
At or below –20 °C
Endotoxin content:
Endotoxin LAL (EU/µg) ≤0,05
Biological activity:
Bioactivity Assay: Proliferation of TF-1, ED₅₀ ≤15 ng/ml, Bioactivity ≥1,0x10³ IU/µg
Gene ID:
P21583
Reconstitution instructions:
Sterile water at 0,1 - 0,5 mg/ml
Endotoxin-free:
N
Carrier-free:
Y
Protease-free:
N
Animal-free:
Y
Protein synonyms:
c-Kit Ligand|KL|mgF|Steel Factor
Protein/peptide name:
CTGrade GMP SCF
Purity:
≥97%
Molecular weight:
18,6 kDa
Sequence:
MEGICRNRVT NNVKDVTKLV ANLPKDYMIT LKYVPGMDVL PSHCWISEMV VQLSDSLTDL LDKFSNISEG LSNYSIIDKL VNIVDDLVEC VKENSSKDLK KSFKSPEPRL FTPEEFFRIF NRSIDAFKDF VVASETSDCV VSSTLSPEKD SRVSVTKPFM LPPVA
Endotoxin level:
Low
Formulation:
10 mM Sodium phosphate, 50 mM Sodium chloride, pH 7,5
Nuclease-free:
N
Grade:
GMP
Shipping temperature:
Ambient
Tested applications:
Bioassay