Immunodensity isolation of untouched plasma cells for multiple myeloma research.

• Fast and easy-to-use
• Requires no special equipment or training
• Untouched, viable cells

The RosetteSep™ Human Multiple Myeloma Cell Enrichment Cocktail is designed to enrich multiple myeloma cells (B cell and plasma cells) from fresh bone marrow aspirates by negative selection. Unwanted cells are targeted for removal with Tetrameric Antibody Complexes recognising CD2, CD14, CD33, CD41, CD45RA, CD66b and glycophorin A on red blood cells (RBCs). When centrifuged over a buoyant density medium such as Lymphoprep™ (STMC07801), the unwanted cells pellet along with the RBCs. The purified multiple myeloma cells are present as a highly enriched population at the interface between the plasma and the buoyant density medium.