Specificaties
- Antibody type:Primary
- Antigen name:ENPP1
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Mouse
- Western blot:Yes
- Environmentally Preferable:
- Epitope:41-140/925
- Form:Liquid
- Gene ID:5167
- Antigen synonyms:PCA1|M6S1|Phosphodiesterase I/nucleotide pyrophosphatase 1|ENPP1|COLED|PDNP1|Ectonucleotide pyrophosphatase/phosphodiesterase family member 1|ARHR2|PC-1|NPP1|NPPS|E-NPP 1|PC1|Plasma-cell membrane glycoprotein PC-1|Membrane component chromosome 6 surface marker 1
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:100 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human ENPP1
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specificaties
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By generating PPi, plays a role in regulating pyrophosphate levels, and functions in bone mineralization and soft tissue calcification. PPi inhibits mineralization by binding to nascent hydroxyapatite (HA) crystals, thereby preventing further growth of these crystals. Preferentially hydrolyses ATP, but can also hydrolyse other nucleoside 5' triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate and diadenosine polyphosphates, and also 3',5'-cAMP to AMP. May also be involved in the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling. Appears to modulate insulin sensitivity and function.
Type: Primary
Antigen: ENPP1
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 41-140/925
Host: Rabbit
Isotype: IgG
Reactivity: Mouse