Human Recombinant BAFF (from E. coli)
B cell-activating factor (BAFF), or B lymphocyte stimulator (BLyS), is a type II member of the tumor necrosis factor (TNF) superfamily. BAFF is expressed as a transmembrane protein on T cells, macrophages, and dendritic cells. The transmembrane domain of BAFF can also be cleaved to produce a soluble protein fragment.
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- Low endotoxin
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BAFF binds to the TNF receptors known as B cell maturation antigen (BCMA), transmembrane activator and CAML interactor (TACI), and BAFF receptor (BAFFR). BAFF is important for the survival and maturation of peripheral B cells. Human BAFF shows activity on mouse splenocytes.
: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
: For research use only.
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