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Human recombinant BCL-xL (from E. coli)
Human recombinant BCL-xL (from E. coli)
  PRSI91-087
 :  ProSci Inc.
 :  
Human recombinant BCL-xL (from E. coli)
  PRSI91-087
 :  ProSci Inc.
 :  

 

  • Pk:
    50 µG
  • Protein/peptide type:
    Recombinant
  • Source:
    E. coli
  • Species:
    Human
  • Tag sequence:
    C-6 His tag
  • Storage conditions:
    Store at −20 °C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
  • Protein synonyms:
    BCLX|Apoptosis Regulator Bcl-X|BCL2L1|BCL2L|Bcl2-L-1|Bcl-2-like Protein 1
  • Protein/peptide name:
    BCL-xL
  • Purity:
    > 95% as determined by reducing SDS-PAGE
  • Molecular weight:
    24.85 kD
  • Sequence:
    Met1-Arg212
  • Formulation:
    Supplied as a 0.2 um filtered solution of 20mM HEPES, 50mM KCl, 20% Glycerol, pH 7.5. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested applications:
    Bioassay

 

 

Bcl-2-Like Protein 1 (BCL2L1) is a member of the Bcl-2 family. BCL2L1 is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. BCL2L1 is a mitochondrial membrane protein. BCL2L1 contains four motifs, BH1, BH2 and BH4. The BH4 motif is required for anti-apoptotic activity. The BH1 and BH2 motifs are required for both heterodimerization with other Bcl-2 family members and for repression of cell death. BCL2L1 regulates cell death by blocking the voltage-dependent anion channnel (VDAC) and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. In addition, BCL2L1 promotes apoptosis.

  • This recombinant protein can be used for biological assays. For research use only.

Fusion-Tag: C-6 His tag