- Antigen name:Prickle Homolog 2
- Antigen symbol:PRICKLE2
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Antigen synonyms:Prickle-like protein 2|EPM5|PRICKLE2
- Storage buffer:PBS containing 0.02% sodium azide
- Immunogen:PRICKLE2 antibody was raised against a 15 amino acid synthetic peptide near the center of human PRICKLE2.
- Tested applications:E, WB, IF
- Purification:Affinity chromatography purified via peptide column
- Size:100 µg
- Pk:100 µG
PRICKLE2 Antibody: PRICKLE2, also known as Pk2 or EPM5, is a member of a highly conserved protein family that function in the noncanonical WNT signaling pathway which regulates intracellular calcium release and planar cell polarity. Both PRICKLE2 and the related protein PRICKLE1 are expressed in postmitotic neurons and promote neurite outgrowth, and both proteins promote neurite outgrowth via the Dishevelled dependent pathway in C1300 cells. PRICKLE2 localizes to the postsynaptic density and interacts with PSD-95 and NMDA receptors. Defects in the gene encoding PRICKLE2 are associated with autosomal recessive progressive myoclonic epilepsy.
Type:
Antigen: PRICKLE2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat