Anti-RUNX3 Rabbit Polyclonal Antibody (Alexa Fluor® 488)
BOSSBS-4848R-A488
: Bioss
- Antibody type:Primary
- Antigen name:Runt-related Transcription Factor 3
- Antigen symbol:RUNX3
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 488
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human
- Cross adsorption:No
- Form:liquid
- Gene ID:864
- Antigen synonyms:AML2|Core-binding factor subunit alpha-3|RUNX3|SL3-3 enhancer factor 1 alpha C subunit|PEBP2A3|Runt-related transcription factor 3|Oncogene AML-2|CBFA3|Polyomavirus enhancer-binding protein 2 alpha C subunit|Acute myeloid leukemia 2 protein|SL3/
- Modification:phospho-Ser338
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Purification:Purified by Protein A
- Pk:100 µl
RUNX3 binds to the core site of murine Leukemia virus, the core sequences in the enhancer of the polyomavirus, and also to the enhancers of the T-cell receptor genes. May be involved in the control of cellular proliferation and/or differentiation (By similarity). Heterodimer of an alpha and a beta subunit. The alpha subunit binds DNA as a monomer and through the Runt domain.DNA-binding is increased by heterodimerization. Interacts with TLE1 and SUV39H1, Subcellular location in Nucleus.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: RUNX3
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 488
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human