- Antibody type:Primary
- Antigen name:Ectonucleotide pyrophosphatase/phosphodiesterase 1
- Antigen symbol:ENPP1
- Clonality:Polyclonal
- Conjugation:Cy5.5®
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Environmentally Preferable:
- Cross adsorption:No
- Form:liquid
- Gene ID:5167
- Antigen synonyms:PCA1|phosphodiesterase I/nucleotide pyrophosphatase 1|M6S1|membrane component|surface marker 1|plasma-cell membrane glycoprotein 1|alkaline phosphodiesterase 1|ENPP1|HGNC:3356|PDNP1|Ly-41 antigen|PC-1|NPP1|NPPS|ectonucleotide pyrophosphatase/phosphodiesterase 1|OTTHUMP00000043194|chromosome 6
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Immunogen:97-150/925
- Purification:Purified by Protein A
- Pk:100 µl
By generating PPi, plays a role in regulating pyrophosphate levels, and functions in bone mineralization and soft tissue calcification. PPi inhibits mineralization by binding to nascent hydroxyapatite (HA) crystals, thereby preventing further growth of these crystals. Preferentially hydrolyzes ATP, but can also hydrolyze other nucleoside 5' triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate and diadenosine polyphosphates, and also 3',5'-cAMP to AMP. May also be involved in the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling. Appears to modulate insulin sensitivity and function.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: ENPP1
Clonality: Polyclonal
Clone:
Conjugation: Cy5.5®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat