About this item
This MAb recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120 kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi's sarcoma, but with a lower specificity.
Type: Primary
Antigen: CD34
Clonality: Monoclonal
Clone: QBEnd/10 HPCA1/763
Conjugation: CF647
Epitope:
Host: Mouse
Reactivity: Human
Isotype: IgGs
Specifications
- Catalog No:
- BNC470904-500
- BNC470904-100
- Antigen symbol:
- CD34
- CD34
- Antigen synonyms:
- Hematopoietic Progenitor Cell Antigen|Mucosialin|HPCA1
- Hematopoietic Progenitor Cell Antigen|Mucosialin|HPCA1
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- CF® 647
- CF® 647
- Clone:
- Clone QBEnd/10 HPCA1/763
- Clone QBEnd/10 HPCA1/763
- Reactivity:
- Human
- Human
- Host:
- Mouse
- Mouse
- Gene ID:
- 374990
- 374990
- Isotype:
- IgGs
- IgGs
- ImmunoChemistry:
- Yes
- Yes
- ImmunoFluorescence:
- Yes
- Yes
- Concentration:
- 0,1 mg/ml
- 0,1 mg/ml
- Storage buffer:
- PBS/0,1% BSA/0,05% azide
- PBS/0,1% BSA/0,05% azide
Specifications
Supplier: VWR Chemicals
Supplier: HEATHROW
Supplier: VWR Collection
Supplier: KIMBERLY CLARK
Supplier: VWR Chemicals
Supplier: VWR Chemicals
Supplier: VWR Collection
Supplier: VWR Collection
Supplier: VWR Chemicals
Supplier: VWR Collection
Supplier: VWR Collection
Supplier: Merck