The Neurotransmitter Transporter Uptake Assay Kit provides a fast, simple and reliable fluorescence-based assay for the detection of dopamine, norepinephrine and serotonin transporter (SERT, NET and DAT, respectively) activity in expressing cells.

• Homogeneous, live-cell fluorescent assay replaces radioactive assays, reducing disposal costs and eliminating associated safety risks
• One-step, homogeneous assay format is amenable to automation and high-throughput screening
• Two assay setup options offer greater flexibility, with endpoint mode for high-throughput applications, or real-time kinetic mode for mechanistic studies

Neurotransmitter transporters play a key role in depression and neurodegenerative diseases (NDD) such as Alzheimer's and Parkinson's. The ability to monitor serotonin, norepinephrine and dopamine neurotransmitter uptake is key to a better understanding of these diseases.