Heparin sodium salt

Supplier: PanReac AppliChem

Heparin sodium salt, solid

Supplier: Abcam

Endogenous glycosaminoglycan with anticoagulant activity. Binds and activates antithrombin III; inhibits binding and and activation of thrombin and Factor Xa. Potentially blocks bone and cartiledge formation. Ligand for ALK oncogenic kinase. Used in the generation of kidney organoids from human pluripotent stem cells. Used in protocol to generate kidney organoids.

Supplier: Thermo Fisher Scientific

Appearance: White to almost white Powder

Supplier: TCI

Heparin sodium salt (from hog intestine)

Supplier: MP Biomedicals

Heparin is a polymer classified as a mucopolysaccharide or a glycosoaminoglycan. It is biosynthesized and stored in mast cells of various mammalian tissues, particularly liver, lung and mucosa. It is made up of repeated disaccharide units consisting of 1,4-linked L-iduronic acid and D-glucosamine. The iduronic acid residues are O-sulfated at position 2, and the glucosamine residues are N-sulfated and O-sulfated at position 6. The repeated block can be interrupted or extended by residues of beta-D-glucuronic acid and 6-O-sulfated N-acetyl-alpha-D-glucosamine.