You searched for: Educational Materials
A comprehensive catalog of education materials, instruments, and tools available through Avantor allows users to more effectively teach subjects of biology, physics, language arts, chemistry, earth science, forensics, math, and environmental studies. Many interdisciplinary kits allow students to match skills across a variety of subjects in order to better absorb key concepts and procedures. Educational materials are designed to be durable and user-friendly for accessibility with users of all levels.
Experimentation kits, diversity of fish proteins
Supplier: EDVOTEK
In this experiment, students study the diversity of fish using pre-stained, lyophilised proteins. Total protein from perch, walleye and salmon is extracted and pre-stained using an indicator dye. Each fish protein sample has a characteristic banding pattern when separated by denaturing SDS-polyacrylamide gel electrophoresis, which can be used to identify the specific species.
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Experimentation kits, in search of the cholesterol gene
Supplier: EDVOTEK
Coronary heart disease and stroke are major causes of death in the Western world. Elevated blood cholesterol levels are a serious risk factor in both conditions. The genetic disease familial hypersholesterolemia (FH) causes an increase in blood levels of the bad form of cholesterol, low density lipoprotein (LDL). In untreated patients with the mutant FH gene, the condition can cause premature death. This experiment introduces the colorimetric enzymatic reaction which is the basis of the clinical cholesterol test. In addition, using agarose gel electrophoresis, students can analyse a simulated genetic screening for a disease.
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Kits: sickle cell gene detection (DNA-based), Ready-to-Load™
Supplier: EDVOTEK
This Ready-to-Load™ kit shows how a restriction enzyme can be used to screen DNA for Sickle Cell Anaemia.
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Experimentation kits, survey of protein diversity (polyacrylamide-based)
Supplier: EDVOTEK
For learning about the diversity of proteins by studying the electrophoretic profiles of various sources. Students separate proteins from bacterial, plant, serum, and milk proteins alongside a standard protein marker.
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DNA fingerprinting kit
Supplier: G-Biosciences
This DNA fingerprinting kit allows students to carry out their own criminal investigation by comparing DNA samples collected from suspects to DNA collected at a pseudo-crime scene.
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Kits: restriction enzyme cleavage patterns of DNA, Ready-to-Load™
Supplier: EDVOTEK
Plasmid and lambda DNA are pre-digested with restriction endonucleases that recognise and cut double-stranded DNA within or near defined base sequences. Digests are separated by agarose gel electrophoresis.
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Transformation with blue and green fluorescent proteins
Supplier: EDVOTEK
The Green Fluorescent Protein (GFP) from the jellyfish Aequorea victoria is used extensively in all areas of science. Many organisms have been transformed with the GFP gene, the gene responsible for bioluminescence in jellyfish. It has proven to be so useful that scientists have mutated it to produce Blue Fluorescent Protein (BFP). In this simple experiment, students transform bacteria either by GFP, BFP or both.
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Kits: family pedigree cancer gene detection, Ready-to-Load™
Supplier: EDVOTEK
In this experiment, students determine a pedigree for a family thought to be carriers of a mutation in their p53 genes. This is followed by a diagnostic agarose gel analysis to diagnose the state of the p53 gene in individual family members.
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Kits: DNA-based screening for smallpox, Ready-to-Load™
Supplier: EDVOTEK
This experiment presents a bioterrorism scenario, with students examining a simulated DNA fingerprinting test for the detection of smallpox.
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What does DNA look like?
Supplier: EDVOTEK
This Lab activity shows students what real chromosomal DNA Looks Like and allows them to explore the procedures involved in DNA extraction.
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Experimentation kits, mitochondrial DNA analysis using PCR
Supplier: EDVOTEK
The mitochondria are thought to have evolved from a symbiotic relationship between prokaryotic and eukaryotic cells. Mitochondria have their own DNA and are only inherited via the maternal line. In this experiment, students amplify two regions of their mitochondrial DNA.
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Experimentation kits, purification of the restriction enzyme Eco RI
Supplier: EDVOTEK
In this experiment, students purify the restriction enzyme, Eco RI. This procedure utilised an ion exchange chromatograph step for Eco RI purification. Column fractions are assayed for the enzyme using Lambda DNA and digestion products are identified by gel electrophoresis. Fractions that contain Eco RI are identified and pooled. The total and specific activities are calculated. Recommended for advanced courses.
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Experimentation kits, DNA fingerprinting - using PCR
Supplier: EDVOTEK
Students can solve a crime using PCR. Plasmid DNA is provided that, when amplified by PCR, provides products that represent individual DNA profiles.
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Kits: detection of mad cow disease, Ready-to-Load™
Supplier: EDVOTEK
Bovine spongiform encephalophathy (BSE), also known as Mad Cow Disease, is a neurodegenerative, fatal condition in cattle. Consuming BSE-infected beef is believed to be the cause of a similar condition in humans, Creutzfeldt-Jakob disease. In this experiment, students examine simulated PCR products from several feed mills, to determine any possible violations of the ban on including animal parts in cattle feed.
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Experimentation kits, PCR-based Alu-Human DNA typing
Supplier: EDVOTEK
Students use primers for a 300 base pair Alu insertion in chromosome 16 (PV92) to determine their own genotype. They can then compare their class results with others around the world over the internet.
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Experimentation kits, determination of protein molecular weight (polyacrylamide-based)
Supplier: EDVOTEK
Using prestained LyphoProteins, subunit molecular weights are determined by analysis using denaturing SDS vertical polyacrylamide gel electrophoresis. Prestained proteins with unknown molecular weights are assigned molecular weights based on the relative mobility of prestained standard protein markers.
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Do onions, strawberries and bananas have DNA?
Supplier: EDVOTEK
Kit allows students to construct DNA models and then extract DNA from onions, strawberries or bananas.
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Experimentation kits, PCR-based VNTR human DNA typing
Supplier: EDVOTEK
In DNA fingerprinting, variable number tandem repeats (VNTR) are used to identify individuals. Using this kit, students type themselves at the D1S80 locus on chromosome 1. This region contains between 14 and 40 copies of a 16 base pair repeat.
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Experimentation kits, exploring biotechnology with green fluorescent protein (GFP)
Supplier: EDVOTEK
Four experimental modules are combined into one experiment to provide a comprehensive biotechnology exploration focusing on the green fluorescent protein (GFP). Bacterial cells are transformed to express the GFP. The transformed cells are then grown and the GFP purified by column chromatography. Finally, the purity of the protein fractions are analysed by SDS polyacrylamide electrophoresis.
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Purification and size determination of green and blue fluorescent proteins
Supplier: EDVOTEK
When bacteria are used to make medicinally useful proteins by transformation, the protein of interest must be separated from all of the other cellular proteins. In this experiment, the unique fluorescent properties of GFP and BFP are used as an assay during their purification from an E. coli extract. The column fractions containing GFP or BFP are identified by fluorescence and then purified. As an optional activity, purified protein fractions can be separated by SDS polyacrylamide gel electrophoresis (SDS-PAGE) to estimate the purity and size of the GFP and BFP proteins.
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Experimentation kits, DNA fingerprinting using restriction enzymes
Supplier: EDVOTEK
This experiment helps teach students about restriction enzyme digests in the context of forensic science. Students cut DNA with restriction enzymes and then compare the banding pattern of the crime scene DNA versus that of two suspects using agarose gel electrophoresis.
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Kits: analysis of Eco RI cleavage patterns of lambda DNA, Ready-to-Load™
Supplier: EDVOTEK
Ready-to-Load™ kit for introducing the use of restriction enzymes as a tool to digest lambda DNA at specific nucleotide sequences.
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Experimentation kits, molecular weight determination of proteins (agarose-based)
Supplier: EDVOTEK
This experiment introduces a simple method to determine protein subunit molecular weights using horizontal electrophoresis. As the protein standards and 'unknowns' are prestained, the separation of proteins can be observed during electrophoresis. Included in the experiment is protein-grade agarose, which provides an alternative to the use of polyacrylamide gels.
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Kits: in search of the sickle cell gene by southern blot, Ready-to-Load™
Supplier: EDVOTEK
Southern blotting is an important technique used widely in clinical genetics and research. By transferring DNA from an agarose gel onto a membrane the method allows the precise analysis and identification of DNA bands on a gel. Using this kit, students use Southern blotting to find a point mutation in the haemoglobin gene indicating Sickle Cell Anaemia.
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Ready-to-Load™ Kits, what is PCR and how does it work?
Supplier: EDVOTEK
This simulation experiment demonstrates the process of DNA amplification by PCR and how the amplified product is detected by separating the reaction mixture by agarose gel electrophoresis.
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Kits: why do people look different?, Ready-to-Load™
Supplier: EDVOTEK
This kit is for teaching students how people's physical traits are a reflection of their genes. In this simulation, students use electrophoresis to separate dyes which represent genetic traits.
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Experimentation kits, ion exchange chromatography
Supplier: EDVOTEK
Most molecules have a net charge within a pH range of 2 to 10. When the pH is altered, the net charge on molecules can change drastically. In this experiment, a mixture of two chemicals is absorbed onto a solid support ion-exchange column and separated during elution under conditions that influence their net charge.
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Experimentation kits, southern blot analysis
Supplier: EDVOTEK
This experiment introduces students to Southern blotting as a tool for DNA fingerprinting in a hypothetical paternity determination. DNA fragments are first separated by agarose gel electrophoresis, then transferred to a nylon membrane and finally visualised by staining.
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Experimentation kits, in search of the 'Kissing Disease'
Supplier: EDVOTEK
Infectious mononucleosis is commonly known as the 'kissing disease'. The causative agent is Epstein-Barr virus (EBV), which can be transmitted through saliva during kissing. In this experiment, students search for the presence of EBV using the ELISA reaction to detect specific viral proteins.
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Kits: mapping of restriction sites on plasmid DNA, Ready-to-Load™
Supplier: EDVOTEK
DNA mapping is a common procedure used to determine the location of genes. In this experiment, DNA markers and pre-digested plasmid DNA fragments are mapped using agarose gel electrophoresis.