Human recombinant TEM7 (from cells)

Catalog # PRSI91-479

Supplier: ProSci Inc.

CAS Number:

Catalog # PRSI91-479

Supplier: ProSci Inc.

CAS Number:

Specifications

Pk:
50 µG
Protein/peptide type:
Recombinant
Source:
Cells
Species:
Human
Tag sequence:
C-6 His tag
Storage conditions:
Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
Protein synonyms:
Plexin Domain-Containing Protein 1|TEM3|TEM7|Tumor Endothelial Marker 7|PLXDC1|Tumor Endothelial Marker 3
Protein/peptide name:
TEM7
Purity:
> 95% as determined by reducing SDS-PAGE
Molecular weight:
46.53 kD
Sequence:
Leu19-Thr426
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, 5% Threhalose, pH 7.2. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Tested applications:
Bioassay

Specifications

About this item

Plexin Domain-Containing Protein 1 (PLXDC1) is a single-pass type I membrane protein that belongs to the plexin family. Secreted PLXDC1 is localized predominantly at the tight junctions of vascular endothelial cells and to a lesser extent at the luminal surface of vascular endothelial cells. PLXDC1 is expressed in fibrovascular membrane with increased expression in individuals with proliferative diabetic retinopathy. It can detect in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. PLXDC1 interacts with NID1 and may also interact with CTTN. It plays a important role in endothelial cell capillary morphogenesis, the proliferation and maintenance of neovascular endothelial cells in the formation of fibrovascular membranes (FVMs).