Anti-PACRG Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog # BOSSBS-9289R-A750

Supplier: Bioss

Catalog # BOSSBS-9289R-A750

Supplier: Bioss

Specifications

Antibody type:
Primary
Antigen name:
PACRG
Clonality:
Polyclonal
Conjugation:
Alexa Fluor® 750
Host:
Rabbit
ImmunoChemistry:
Yes
ImmunoFluorescence:
Yes
Isotype:
IgG
Reactivity:
Human,
Rat,
Mouse
Western blot:
Yes
Epitope:
41-140/296
Form:
Liquid
Gene ID:
135138
Antigen synonyms:
PARK2CRG|PARK2 coregulated|PARK 2 coregulated|Molecular chaperone/chaperonin binding protein|GLUP|Parkin co regulated gene protein|Parkin Co-regulated Gene|PARK 2 co regulated|Parkin coregulated gene protein|PARK2 co regulated|PACRG_HUMAN|RP3 495O10.2
Modification:
Unmodified
Storage buffer:
Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
Storage temperature:
Store at ‒20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Concentration:
1 µg/µl
Shipping temperature:
4 °C
Immunogen:
KLH conjugated synthetic peptide derived from human PACRG
Purification:
Purified by Protein A
Pack type:
Vial
Pk:
100 µl

Specifications

About this item

The deduced 257 amino acid protein PACRG (Parkin co-regulated gene) shows potential links to the ubiquitin/proteasome system. PACRG and Parkin are attached in a head-to-head arrangement on opposite DNA strands and share a common 5' flanking promoter region. The PACRG gene maps to chromosome 6q26; Northern blot analysis detects PACRG expression in all tissues examined except placenta. Using a positional cloning strategy in 197 Vietnamese leprosy simplex families (i.e. families with two unaffected parents and one affected child), significant connections between leprosy and 17 markers in the 5' regulatory region that PARK2 and PACRG share were observed. Possession of two or more of the 17 risk alleles is highly predictive of leprosy.PACRG is a gene located very close to parkin, in reverse orientation on the chromosome. It is thought to be co-transcribed with parkin by a bi-directional promoter between the two genes.

Type: Primary
Antigen: PACRG
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 41-140/296
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse; Rat