Anti-TRPM8 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog # BOSSBS-9045R-HRP

Supplier: Bioss

Catalog # BOSSBS-9045R-HRP

Supplier: Bioss

Specifications

Antibody type:
Primary
Antigen name:
Transient Receptor Potential Cation Channel Subfamily M member 8
Antigen symbol:
TRPM8
Clonality:
Polyclonal
Conjugation:
HRP (Horseradish Peroxidase)
Host:
Rabbit
ImmunoChemistry:
Yes
Isotype:
IgG
Reactivity:
Human,
Rat,
Mouse
Western blot:
Yes
Environmentally Preferable:
Cross adsorption:
No
Form:
liquid
Gene ID:
79054
Antigen synonyms:
Transient receptor potential cation channel subfamily M member 8|TRPP8|LTrpC6|transient receptor potential-p8|MGC2849|LTRPC6|Trp-p8|long transient receptor potential channel 6
Storage buffer:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% Gentamicin. Store at 4°C for 12 months.
Storage temperature:
Store at –20 °C for 12 months
Concentration:
1 μg/μl
Shipping temperature:
4°C
Purification:
Purified by Protein A
Pk:
100 µl

Specifications

About this item

Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage-dependent gating. Activated upon depolarization, changes in temperature resulting in graded shifts of its voltage-dependent activation curves. The chemical agonists menthol functions as a gating modifier, shifting activation curves towards physiological membrane potentials. Temperature sensitivity arises from a tenfold difference in the activation energies associated with voltage-dependent opening and closing.

Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500

Type: Primary
Antigen: TRPM8
Clonality: Polyclonal
Clone:
Conjugation: HRP (Horseradish Peroxidase)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat