Specifications
- Type antilichaam:Primair
- antigeen symbool:KDM5B
- Clonality:Polyklonaal
- Conjugatie:Alexa Fluor® 555
- Host:Rabbit
- ImmunoChemie:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Kruisadsorptie:No
- Formulier:liquid
- Gen-ID:10765
- Antigeen synoniemen:PLU1|JARID1B|CT31|RBP2-H1|PUT1|RBBP2H1A|PPP1R98|PLU-1
- Opslagbuffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Opslagtemperatuur:Store at 4°C for 12 months
- Concentratie:1 μg/μl
- Shipping temperature:4°C
- Immunogeen:80-130/1544
- Purification:Purified by Protein A
- VPE:100 µl
Specifications
About this item
Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By similarity).
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: KDM5B
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 555
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
Supplier: VWR Chemicals
Supplier: HEATHROW
Supplier: VWR Chemicals
Supplier: VWR Chemicals
Supplier: KIMBERLY CLARK
Supplier: VWR Collection
Supplier: VWR Collection
Supplier: VWR Collection
Supplier: VWR Chemicals
Supplier: Merck
Supplier: VWR Collection
Supplier: VWR Collection